Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | F10 | P00742 | 16/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6152664 | 0.89 | F10 (0.65) | ALDH1A1L3MBTL1F10ATMMAPT | |
| SCHEMBL5735457 | 0.87 | F10 (0.58) | F10ATMF2 | |
| SCHEMBL5326524 | 0.85 | L3MBTL1 (0.54) | ALDH1A1L3MBTL1F10ATMMAPT | |
| SCHEMBL4900354 | 0.85 | F10 (0.65) | F10 | |
| SCHEMBL5322343 | 0.84 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1F10ATMMAPT | |
| SCHEMBL5326485 | 0.84 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1F10ATMMAPT | |
| SCHEMBL5323222 | 0.83 | L3MBTL1 (0.47) | ALDH1A1L3MBTL1F10ATMMAPT | |
| SCHEMBL5733653 | 0.82 | F10 (0.57) | F10ATMF2 | |
| SCHEMBL5737277 | 0.81 | F10 (0.56) | F10ATMF2 | |
| SCHEMBL5193868 | 0.81 | ATM (0.71) | L3MBTL1F10ATMF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082303-B1 | HETEROCYCLIC DERIVATIVES WHICH INHIBIT FACTOR XA | ASTRAZENECA AB (SE) | 2005-01-26 | — | — | EP | disclosed |
| US-6395731-B1 | ANTICOAGULANTS | ASTRAZENECA AB (SE) | 2002-05-28 | — | — | US | disclosed |
| EP-1082303-A1 | HETEROCYCLIC DERIVATIVES WHICH INHIBIT FACTOR XA | AstraZeneca AB (SE) | 2001-03-14 | — | — | EP | disclosed |
| WO-1999057099-A1 | HETEROCYCLIC DERIVATIVES WHICH INHIBIT FACTOR XA | ASTRAZENECA AB (SE) | 1999-11-11 | — | — | WO | disclosed |