Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5326524 | 0.88 | L3MBTL1 (0.54) | ALDH1A1L3MBTL1MAPTATMF10 | |
| SCHEMBL6152346 | 0.84 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1MAPTATMF10 | |
| SCHEMBL6152664 | 0.84 | F10 (0.65) | ALDH1A1L3MBTL1MAPTATMF10 | |
| SCHEMBL5326485 | 0.83 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1MAPTATMF10 | |
| SCHEMBL5327745 | 0.83 | MAPT (0.52) | ALDH1A1L3MBTL1MAPTF10LMNA | |
| SCHEMBL5323222 | 0.82 | L3MBTL1 (0.47) | ALDH1A1L3MBTL1MAPTATMF10 | |
| SCHEMBL14095701 | 0.77 | F10 (0.50) | ALDH1A1L3MBTL1MAPTATMF10 | |
| SCHEMBL4900354 | 0.75 | F10 (0.65) | F10 | |
| SCHEMBL5327115 | 0.72 | GHSR (0.50) | L3MBTL1MAPTATMF10MEN1 | |
| SCHEMBL5324846 | 0.72 | HRH3 (0.54) | L3MBTL1MAPTATMF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007008145-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVES AS INHIBITORS OF FACTOR XA | ASTRAZENECA AB (SE) | 2007-01-18 | — | — | WO | disclosed |