SCHEMBL6152494

SCHEMBL6152494

COc1ccc2c(c1)c(=O)c1ccccc1n2-c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.58
MAPT P10636 4/20 0.56
HTT P42858 2/20 0.56
L3MBTL1 Q9Y468 5/20 0.53
ALDH1A1 P00352 4/20 0.53
KMT2A Q03164 3/20 0.53
HPGD P15428 3/20 0.53
MEN1 O00255 2/20 0.53
HSD17B10 Q99714 1/20 0.53
PTGS2 P35354 1/20 0.52
P2RX4 Q99571 1/20 0.50
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
ABCG2 Q9UNQ0 1/20 0.49
MAOA P21397 1/20 0.49
LMNA P02545 1/20 0.49
ATM Q13315 1/20 0.49
TSHR P16473 1/20 0.47
MAPK1 P28482 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL533613 0.88 KDM4E (0.68) KDM4EMAPTHTTL3MBTL1ALDH1A1
SCHEMBL19879303 0.86 MAPT (0.65) KDM4EMAPTL3MBTL1ALDH1A1KMT2A
SCHEMBL19368319 0.86 KDM4E (0.64) KDM4EMAPTHTTL3MBTL1ALDH1A1
SCHEMBL3347452 0.84 PTGS2 (0.54) KDM4EMAPTHTTL3MBTL1ALDH1A1
SCHEMBL6152266 0.83 L3MBTL1 (0.76) KDM4EMAPTHTTL3MBTL1ALDH1A1
SCHEMBL27836314 0.83 P2RX4 (0.53) KDM4EMAPTHTTL3MBTL1ALDH1A1
SCHEMBL30352484 0.81 MAPT (0.68) KDM4EMAPTHTTL3MBTL1ALDH1A1
SCHEMBL28988538 0.81 MAPT (0.68) KDM4EMAPTHTTL3MBTL1ALDH1A1
SCHEMBL25613235 0.81 KDM4E (0.60) KDM4EMAPTHTTL3MBTL1ALDH1A1
SCHEMBL16171589 0.81 KDM4E (0.59) KDM4EMAPTHTTL3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030044646-A1 Electroluminescent (EL) devices XEROX CORPORATION 2003-03-06 US claimed
US-6479172-B2 PERFORMANCE, THERMOSTABILITY XEROX CORPORATION 2002-11-12 US claimed
US-20020132134-A1 Electroluminescent (EL) devices XEROX CORPORATION 2002-09-19 US claimed
EP-2597128-B1 Novel blue emitters for use in organic electroluminescence devices LG DISPLAY CO LTD (KR) 2017-07-05 EP disclosed
US-9085729-B2 Blue emitters for use in organic electroluminescence devices LG DISPLAY CO., LTD. (KR) 2015-07-21 US disclosed
EP-1580250-B1 Novel blue emitters for use in organic electroluminescence devices LG DISPLAY CO LTD (KR) 2014-04-30 EP disclosed
EP-2597128-A1 Novel blue emitters for use in organic electroluminescence devices LG Display Co., Ltd. (KR) 2013-05-29 EP disclosed
EP-1580250-A2 Novel blue emitters for use in organic electroluminescence devices Xerox Corporation (US) 2005-09-28 EP disclosed
US-20050175857-A1 Element including fluorescent 1,1'-binaphthyl derivative; uniform luminescence, saturated color; thermal stability; performance; vacuum deposition thin films; enhanced charge transporting, reduced driving voltage XEROX CORPORATION (US) 2005-08-11 US disclosed
US-6562485-B2 Electroluminescent (EL) devices XEROX CORPORATION 2003-05-13 US disclosed
US-20030044646-A1 Electroluminescent (EL) devices XEROX CORPORATION 2003-03-06 US disclosed
US-6479172-B2 PERFORMANCE, THERMOSTABILITY XEROX CORPORATION 2002-11-12 US disclosed
US-20020132134-A1 Electroluminescent (EL) devices XEROX CORPORATION 2002-09-19 US disclosed