SCHEMBL6152607

SCHEMBL6152607

CC(=O)c1[c]ccc(C(C)=O)c1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
MAOB P27338 1/20 0.39
CYP2A6 P11509 1/20 0.38
CA5A P35218 1/20 0.38
ALDH1A1 P00352 4/20 0.38
TDP1 Q9NUW8 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
PKM P14618 1/20 0.37
CREBBP Q92793 1/20 0.37
LMNA P02545 1/20 0.37
MAPK1 P28482 1/20 0.37
PRKCI P41743 1/20 0.36
HPGD P15428 1/20 0.36
S100A4 P26447 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4290947 0.83 CA12 (0.46) MAPTRAB9AMEN1KMT2AALDH1A1
SCHEMBL8413574 0.83 ATM (0.40) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL4064595 0.78 CYP2A6 (0.42) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL22207455 0.78 CA5A (0.38) MAPTMEN1KMT2AMAOBCA5A
SCHEMBL11336223 0.78 CYP2A6 (0.38) MAPTNPC1RAB9AKMT2AMAOB
SCHEMBL3391247 0.77 ALDH1A1 (0.41) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL6975368 0.77 TDP1 (0.41) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL7584988 0.77 MAOB (0.38) MAOBALDH1A1MAPK1HPGD
SCHEMBL6170690 0.77 ALDH1A1 (0.36) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL561510 0.77 NPC1 (0.38) MAPTNPC1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110669058-A Tricyclic quinolone carboxylic acid and preparation method thereof 江西农业大学 2020-01-10 CN claimed
CN-110669058-A Tricyclic quinolone carboxylic acid and preparation method thereof 江西农业大学 2020-01-10 CN disclosed
EP-1037106-B1 Color diffusion transfer photographic material FUJI PHOTO FILM CO LTD (JP) 2005-01-26 EP disclosed
EP-1037106-A1 Color diffusion transfer photographic material FUJI PHOTO FILM CO., LTD. (JP) 2000-09-20 EP disclosed
EP-0609058-B1 Hexahydronaphthalene ester derivatives, their preparation and their therapeutic uses SANKYO CO (JP) 1998-12-09 EP disclosed
EP-0865434-A1 COMPOUNDS AND METHODS OF USE TO TREAT INFECTIOUS DISEASES THE PICOWER INSTITUTE FOR MEDICAL RESEARCH (US) 1998-09-23 EP disclosed
EP-0865434-A4 1998-09-23 EP disclosed
EP-0644458-B1 Infrared sensitive silver halide phototographic elements IMATION CORP (US) 1998-08-12 EP disclosed
US-5792840-A SUBSTITUTED GLUCOPYRANOSYL PHOSPHATES SANKYO COMPANY, LIMITED (JP) 1998-08-11 US disclosed
EP-0440947-B1 Infrared sensitive silver halide photographic elements MINNESOTA MINING & MFG (US) 1997-05-28 EP disclosed
US-4886736-A COUPLERS AND COMPOUND CAPABLE OF RELEASING PHOTOGRAPHICALLY USEFUL GROUP UPON REDUCTION FUJI PHOTO FILM CO., LTD. (JP) 1989-12-12 US disclosed
US-4877720-A PHOTOGRAPHIC POLYMER WHICH UNDERGOES REDUCTION UPON DEVELOPMENT FUJI PHOTO FILM CO., LTD. (JP) 1989-10-31 US disclosed
EP-0334362-A2 Heat developable color light-sensitive material Fuji Photo Film Co., Ltd. (JP) 1989-09-27 EP disclosed
US-4840887-A USEFUL GROUP RELEASED BY CLEAVAGE BETWEEN SULFONYL GROUP AND A NITROGEN, SULFUR OR OXYGEN ATOM; STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1989-06-20 US disclosed
US-4820622-A RELEASING DIFFUSIBLE DYE IN ALKALINE SYSTEM AFTER HALIDE REDUCTION FUJI PHOTO FILM CO., LTD. (JP) 1989-04-11 US disclosed
EP-0306833-A2 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1989-03-15 EP disclosed
US-4783396-A Silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1988-11-08 US disclosed
EP-0280252-A2 Silver halide photographic material and method for forming super high contrast image therewith FUJI PHOTO FILM CO., LTD. (JP) 1988-08-31 EP disclosed
EP-0263229-A1 Phenol derivatives, their preparation and the use thereof OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 1988-04-13 EP disclosed
EP-0220746-A2 Silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1987-05-06 EP disclosed