Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL142939 | 0.81 | TSHR (0.40) | ALDH1A1MAPK1GAAMAPTRAB9A | |
| SCHEMBL425996 | 0.79 | PARP1 (0.48) | ALDH1A1SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL422919 | 0.79 | CA1 (0.47) | ALDH1A1SMN1; SMN2MAPK1GAANPC1 | |
| SCHEMBL426458 | 0.79 | HDAC6 (0.46) | SMN1; SMN2GAAHPGD | |
| SCHEMBL425921 | 0.79 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2KMT2AHPGD | |
| SCHEMBL6152607 | 0.77 | MAPT (0.39) | ALDH1A1SMN1; SMN2MAPK1NPC1MAPT | |
| SCHEMBL4064595 | 0.77 | CYP2A6 (0.42) | ALDH1A1SMN1; SMN2MAPK1NPC1MAPT | |
| SCHEMBL561510 | 0.75 | NPC1 (0.38) | ALDH1A1SMN1; SMN2NPC1MAPTRAB9A | |
| SCHEMBL6975368 | 0.75 | TDP1 (0.41) | ALDH1A1SMN1; SMN2NPC1MAPTRAB9A | |
| SCHEMBL2920883 | 0.75 | L3MBTL1 (0.55) | ALDH1A1SMN1; SMN2MAPK1GAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010514-B1 | 3-(PYRIDIN-2-YL)-[1,2,4]-TRIAZINES FOR USE AS FUNGICIDES | BASF SE (DE) | 2010-12-29 | — | — | EP | disclosed |
| CN-101528730-A | Substituted imidazoles as bombesin receptor subtype-3 modulators | MERCK & CO INC (US) | 2009-09-09 | — | — | CN | disclosed |
| CN-101460479-A | 3-(pyridin-2-yl)-[1,2,4]-triazines for use as fungicides | BASF SE (DE) | 2009-06-17 | — | — | CN | disclosed |
| CN-101460475-A | 2- (pyridin-2-yl) -pyrimidines as fungicides | BASF SE (DE) | 2009-06-17 | — | — | CN | disclosed |
| US-20090111692-A1 | 3-(Pyridin-2-Yl)-[1,2,4]-Triazines as Fungicides | BASF AKTIENGESELLSCHAFT (DE) | 2009-04-30 | — | — | US | disclosed |
| US-20090105072-A1 | 2-(Pyridin-2-Yl)-Pyrimidines for Use as Fungicides | BASF SE (DE) | 2009-04-23 | — | — | US | disclosed |
| EP-2010515-A1 | 2-(PYRIDIN-2-YL)-PYRIMIDINES FOR USE AS FUNGICIDES | BASF SE (DE) | 2009-01-07 | — | — | EP | disclosed |
| EP-2010514-A1 | 3-(PYRIDIN-2-YL)-[1,2,4]-TRIAZINES FOR USE AS FUNGICIDES | BASF SE (DE) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007116079-A1 | 2-(PYRIDIN-2-YL)-PYRIMIDINES FOR USE AS FUNGICIDES | BASF SE (DE) | 2007-10-18 | — | — | WO | disclosed |
| WO-2007116078-A1 | 3-(PYRIDIN-2-YL)-[1,2,4]-TRIAZINES FOR USE AS FUNGICIDES | BASF SE (DE) | 2007-10-18 | — | — | WO | disclosed |
| US-20060063820-A1 | 2,6-dihalo-4-(3,3-dichloro-allyloxy)-benzylalcohole derivatives having insecticidal and acaricidal properties | SYNGENTA CROP PROTECTION, INC. | 2006-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090111692-A1 | 3-(Pyridin-2-Yl)-[1,2,4]-Triazines as Fungicides | CBR3, CBR1, TH | ALDH1A1 562/4885SMN1; SMN2 4404/4885MAPK1 2424/4885 |
| US-20060063820-A1 | 2,6-dihalo-4-(3,3-dichloro-allyloxy)-benzylalcohole derivatives having insecticidal and acaricidal properties | DDT, RER1, F7 | ALDH1A1 1735/4885SMN1; SMN2 731/4885MAPK1 1461/4885 |
| US-20090105072-A1 | 2-(Pyridin-2-Yl)-Pyrimidines for Use as Fungicides | CBR3, CBR1, CNPY2 | ALDH1A1 1539/4885SMN1; SMN2 4310/4885MAPK1 3777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.