Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27860665 | 0.81 | TSHR (0.40) | MAPTMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL4286215 | 0.79 | CA1 (0.47) | TDP1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL6152607 | 0.77 | MAPT (0.39) | TDP1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL4064595 | 0.77 | CYP2A6 (0.42) | TDP1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL561510 | 0.75 | NPC1 (0.38) | TDP1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL3391247 | 0.75 | ALDH1A1 (0.41) | TDP1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL3393204 | 0.75 | L3MBTL1 (0.55) | TDP1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL17688358 | 0.74 | CA12 (0.51) | NPC1RAB9AKMT2ATSHRALDH1A1 | |
| SCHEMBL10387887 | 0.73 | HSD17B3 (0.49) | — | |
| SCHEMBL9667627 | 0.72 | PKM (0.46) | TDP1NPC1RAB9AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3206683-A1 | NOVEL METHODS, COMPOUNDS, AND COMPOSITIONS FOR ANESTHESIA | The Board of Trustees of the Leland Stanford Junior University (US) | 2017-08-23 | — | — | EP | claimed |
| WO-2016061538-A1 | NOVEL METHODS, COMPOUNDS, AND COMPOSITIONS FOR ANESTHESIA | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2016-04-21 | — | — | WO | claimed |
| CN-102827091-A | Triazine mercapto derivate as well as preparation method and application thereof | UNIV SHANDONG | 2012-12-19 | — | — | CN | claimed |
| CN-102276535-A | Azazine mercaptoacetamide derivative and preparation method and application thereof | — | 2011-12-14 | — | — | CN | claimed |
| US-20190106387-A1 | NOVEL METHODS, COMPOUNDS, AND COMPOSITIONS FOR ANESTHESIA | THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS | 2019-04-11 | — | — | US | disclosed |
| US-20180022698-A1 | NOVEL METHODS, COMPOUNDS, AND COMPOSITIONS FOR ANESTHESIA | THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS | 2018-01-25 | — | — | US | disclosed |
| EP-3206683-A1 | NOVEL METHODS, COMPOUNDS, AND COMPOSITIONS FOR ANESTHESIA | The Board of Trustees of the Leland Stanford Junior University (US) | 2017-08-23 | — | — | EP | disclosed |
| WO-2016061538-A1 | NOVEL METHODS, COMPOUNDS, AND COMPOSITIONS FOR ANESTHESIA | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2016-04-21 | — | — | WO | disclosed |
| CN-102827091-B | Triazine mercapto derivate as well as preparation method and application thereof | UNIV SHANDONG | 2014-12-17 | — | — | CN | disclosed |
| CN-102827091-A | Triazine mercapto derivate as well as preparation method and application thereof | UNIV SHANDONG | 2012-12-19 | — | — | CN | disclosed |
| CN-102276535-A | Azazine mercaptoacetamide derivative and preparation method and application thereof | — | 2011-12-14 | — | — | CN | disclosed |
| EP-1343756-A2 | 1-ARYL- OR 1-ALKYLSULFONYL-HETEROCYCLYLBENZAZOLES AS 5-HYDROXYTRYPTAMINE-6 LIGANDS | Wyeth (US) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002036562-A2 | 1-ARYL- OR 1-ALKYLSULFONYL-HETEROCYCLYLBENZAZOLES AS 5-HYDROXYTRYPTAMINE-6 LIGANDS | WYETH (US) | 2002-05-10 | — | — | WO | disclosed |
| CN-1070863-C | Phosphonic diester derivatives | OTSUKA PHARMA CO LTD (JP) | 2001-09-12 | — | — | CN | disclosed |
| US-5985858-A | TREATING AND PREVENTING HYPERLIPIDEMIA, DIABETES AND CATARACT, OR AS AN ANTITUMOR AGENT | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1999-11-16 | — | — | US | disclosed |
| CN-1206419-A | Phosphonic acid diester derivatives | OTSUKA PHARMA CO LTD (JP) | 1999-01-27 | — | — | CN | disclosed |
| EP-0882730-A1 | PHOSPHONIC ACID DIESTER DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1998-12-09 | — | — | EP | disclosed |
| CN-1022632-C | Carboxamide compounds, process for preparing same and pharmaceutical composition containing same | OTSUKA PHARMA CO LTD (JP) | 1993-11-03 | — | — | CN | disclosed |
| US-4971957-A | ANTILIPEMIC AGENTS, ANTICHOLESTEROL AGENTS, BENZENECARBOXAMIDOPHOSPHONATES OR BENZENETHIOCARBOXAMIDOPHOSPHONATES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1990-11-20 | — | — | US | disclosed |
| CN-1040029-A | Carboxylic acid amide compounds and preparation method thereof and contain the pharmaceutical composition of this carboxylic acid amine compound | OTSUKA PHARMA CO LTD (JP) | 1990-02-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180022698-A1 | NOVEL METHODS, COMPOUNDS, AND COMPOSITIONS FOR ANESTHESIA | GABRA5, GABRA4, GABRA6 | TDP1 3379/4885NPC1 3821/4885RAB9A 3176/4885 |
| US-20190106387-A1 | NOVEL METHODS, COMPOUNDS, AND COMPOSITIONS FOR ANESTHESIA | GABRA5, GABRA4, GABRA6 | TDP1 3379/4885NPC1 3821/4885RAB9A 3176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.