SCHEMBL6152733

SCHEMBL6152733

O=C(O)C(=NOCCOc1cc(Cl)cc(Cl)c1)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 1/20 0.46
F2 P00734 7/20 0.43
KDM4E B2RXH2 3/20 0.39
POLB P06746 1/20 0.39
PKM P14618 1/20 0.39
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ENPP2 Q13822 1/20 0.37
MEN1 O00255 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
KMT2A Q03164 1/20 0.37
PARP10 Q53GL7 1/20 0.37
HRH3 Q9Y5N1 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6153118 0.86 PKM (0.53) KDM4EPKMLMNAMAPTSMN1; SMN2
SCHEMBL6152765 0.73 LMNA (0.51) POLBLMNASMN1; SMN2L3MBTL1MEN1
SCHEMBL11541350 0.73 SMN1; SMN2 (0.46) KDM4EPOLBLMNAMAPTSMN1; SMN2
SCHEMBL11541352 0.73 SMN1; SMN2 (0.46) KDM4EPOLBLMNAMAPTSMN1; SMN2
SCHEMBL6152731 0.70 MRGPRX4 (0.43) MRGPRX4F2KDM4ELMNAMAPT
SCHEMBL8527416 0.69 KDM4E (0.38) KDM4EPKMLMNAMAPTL3MBTL1
SCHEMBL11480233 0.68 KMT2A (0.50) LMNASMN1; SMN2TDP1L3MBTL1MEN1
SCHEMBL11480227 0.68 KMT2A (0.50) LMNASMN1; SMN2TDP1L3MBTL1MEN1
SCHEMBL8020309 0.67 POLB (0.46) POLBMAPTSMN1; SMN2L3MBTL1NPC1
SCHEMBL8020305 0.67 POLB (0.46) POLBMAPTSMN1; SMN2L3MBTL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1494991-A1 ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES Isagro Ricerca S.r.l. (IT) 2005-01-12 EP disclosed
WO-2003087032-A1 ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES ISAGRO RICERCA S.R.L. (IT) 2003-10-23 WO disclosed