Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | PPARA | Q07869 | 3/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22758100 | 0.87 | CYP2C19 (0.51) | LMNAPPARAPPARGKMT2ASMN1; SMN2 | |
| SCHEMBL11243827 | 0.87 | LMNA (0.49) | LMNAPPARAPPARGKMT2ASMN1; SMN2 | |
| SCHEMBL11243831 | 0.87 | CYP2C19 (0.51) | LMNAPPARAPPARGKMT2ASMN1; SMN2 | |
| SCHEMBL11243823 | 0.87 | LMNA (0.49) | LMNAPPARAPPARGKMT2ASMN1; SMN2 | |
| SCHEMBL11541352 | 0.86 | SMN1; SMN2 (0.46) | LMNAKMT2ASMN1; SMN2CES2CES1 | |
| SCHEMBL11541350 | 0.86 | SMN1; SMN2 (0.46) | LMNAKMT2ASMN1; SMN2CES2CES1 | |
| SCHEMBL6153118 | 0.80 | PKM (0.53) | LMNAPPARASMN1; SMN2MAPK1L3MBTL1 | |
| SCHEMBL22946578 | 0.78 | PPARG (0.59) | LMNAPPARAPPARGSMN1; SMN2MAPK1 | |
| SCHEMBL11228210 | 0.78 | ESR1 (0.45) | LMNAPPARAPPARGCES2CES1 | |
| SCHEMBL11228208 | 0.78 | ESR1 (0.45) | LMNAPPARAPPARGCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1494991-A1 | ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES | Isagro Ricerca S.r.l. (IT) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003087032-A1 | ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES | ISAGRO RICERCA S.R.L. (IT) | 2003-10-23 | — | — | WO | disclosed |