Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15739433 | 0.98 | NAAA (0.56) | NAAAEPHX1HDAC6HDAC8SMN1; SMN2 | |
| SCHEMBL19301621 | 0.93 | NAAA (0.52) | NAAAEPHX1HDAC6HDAC8SMN1; SMN2 | |
| SCHEMBL3987516 | 0.89 | — | — | |
| SCHEMBL3184451 | 0.89 | NAAA (0.66) | NAAAEPHX1HDAC6HDAC8SMN1; SMN2 | |
| SCHEMBL20794256 | 0.88 | NAAA (0.66) | NAAAEPHX1HDAC6HDAC8SMN1; SMN2 | |
| SCHEMBL15426780 | 0.88 | NAAA (0.66) | NAAAEPHX1HDAC6HDAC8SMN1; SMN2 | |
| SCHEMBL17172545 | 0.83 | NAAA (0.82) | NAAAEPHX1HDAC6HDAC8SMN1; SMN2 | |
| SCHEMBL6136977 | 0.82 | EPHX1 (0.63) | NAAAEPHX1HDAC6HDAC8SMN1; SMN2 | |
| SCHEMBL13712654 | 0.82 | NAAA (0.69) | NAAAEPHX1HDAC6HDAC8SMN1; SMN2 | |
| SCHEMBL16512798 | 0.82 | NAAA (0.42) | NAAAEPHX1SMN1; SMN2HSD17B10KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112752757-B | Tyrosine amide derivatives as RHO-kinase inhibitors | 奇斯药制品公司 | 2024-01-12 | — | — | CN | claimed |
| US-7632911-B2 | Liquid modified diphenylmethane diisocyanates | BAYER MATERIALSCIENCE LLC (US) | 2009-12-15 | — | — | US | claimed |
| WO-2008060411-A2 | NEW LIQUID MODIFIED DIPHENYLMETHANE DIISOCYANATES | BAYER MATERIALSCIENCE LLC (US) | 2008-05-22 | — | — | WO | claimed |
| US-20080114186-A1 | New liquid modified diphenylmetilane diisocyanates | BAYER MATERIALSCIENCE LLC | 2008-05-15 | — | — | US | claimed |
| CN-112752757-B | Tyrosine amide derivatives as RHO-kinase inhibitors | 奇斯药制品公司 | 2024-01-12 | — | — | CN | disclosed |
| US-20170166548-A1 | Substituted chroman-6-yloxy-cycloalkanes and their use as pharmaceuticals | SANOFI (FR) | 2017-06-15 | — | — | US | disclosed |
| US-9440941-B2 | Substituted chroman-6-yloxy-cycloalkanes and their use as pharmaceuticals | SANOFI (FR) | 2016-09-13 | — | — | US | disclosed |
| US-20160016928-A1 | Substituted chroman-6-yloxy-cycloalkanes and their use as pharmaceuticals | SANOFI (FR) | 2016-01-21 | — | — | US | disclosed |
| US-8129519-B2 | Derivatives of fluorene, anthracene, xanthene, dibenzosuberone and acridine and uses thereof | ALLERGAN SALES, LLC | 2012-03-06 | — | — | US | disclosed |
| US-20110039981-A1 | EPOXY RESINS DERIVED FROM NON-SEED OIL BASED ALKANOLAMIDES AND A PROCESS FOR PREPARING THE SAME | DOW GLOBAL TECHNOLOGIES LLC | 2011-02-17 | — | — | US | disclosed |
| EP-2283059-A1 | EPOXY RESINS DERIVED FROM NON-SEED OIL BASED ALKANOLAMIDES AND A PROCESS FOR PREPARING THE SAME | Dow Global Technologies Inc. (US) | 2011-02-16 | — | — | EP | disclosed |
| US-20100137354-A1 | DERIVATIVES OF FLUORENE, ANTHRACENE, XANTHENE, DIBENZOSUBERONE AND ACRIDINE AND USES THEREOF | ALLERGAN SALES, LLC | 2010-06-03 | — | — | US | disclosed |
| US-20100041794-A1 | HYDROXYL-TERMINATED OR CARBOXYLIC ACID-TERMINATED REACTIVE MONOMER COMPOSITIONS, THEIR PREPARATION AND THEIR USE | DOW GLOBAL TECHNOLOGIES LLC | 2010-02-18 | — | — | US | disclosed |
| US-7632911-B2 | Liquid modified diphenylmethane diisocyanates | BAYER MATERIALSCIENCE LLC (US) | 2009-12-15 | — | — | US | disclosed |
| WO-2009143037-A1 | EPOXY RESINS DERIVED FROM NON-SEED OIL BASED ALKANOLAMIDES AND A PROCESS FOR PREPARING THE SAME | DOW GLOBAL TECHNOLOGIES INC. (US) | 2009-11-26 | — | — | WO | disclosed |
| EP-2121581-A2 | HYDROXYL-TERMINATED OR CARBOXYLIC ACID- TERMINATED REACTIVE MONOMER COMPOSITIONS, THEIR PREPARATION AND THEIR USE | Dow Global Technologies Inc. (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008088624-A2 | HYDROXYL-TERMINATED OR CARBOXYLIC ACID- TERMINATED REACTIVE MONOMER COMPOSITIONS, THEIR PREPARATION AND THEIR USE | DOW GLOBAL TECHNOLOGIES INC. (US) | 2008-07-24 | — | — | WO | disclosed |
| WO-2008060411-A2 | NEW LIQUID MODIFIED DIPHENYLMETHANE DIISOCYANATES | BAYER MATERIALSCIENCE LLC (US) | 2008-05-22 | — | — | WO | disclosed |
| US-20080114186-A1 | New liquid modified diphenylmetilane diisocyanates | BAYER MATERIALSCIENCE LLC | 2008-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160016928-A1 | Substituted chroman-6-yloxy-cycloalkanes and their use as pharmaceuticals | RYR2, RYR1, CACNA1E | NAAA 3021/4885EPHX1 445/4885HDAC6 2351/4885 |
| US-20170166548-A1 | Substituted chroman-6-yloxy-cycloalkanes and their use as pharmaceuticals | RYR2, RYR1, CACNA1E | NAAA 3035/4885EPHX1 450/4885HDAC6 2336/4885 |
| US-20100137354-A1 | DERIVATIVES OF FLUORENE, ANTHRACENE, XANTHENE, DIBENZOSUBERONE AND ACRIDINE AND USES THEREOF | WNT1, CTNND1, CTNNB1 | NAAA 3387/4885EPHX1 4256/4885HDAC6 1814/4885 |
| US-20080114186-A1 | New liquid modified diphenylmetilane diisocyanates | DDT, DIMT1, QDPR | NAAA 1590/4885EPHX1 2391/4885HDAC6 3556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.