Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6152020 | 0.87 | ACLY (0.43) | NPSR1POLBPKMTDP1MAPT | |
| SCHEMBL13794381 | 0.84 | POLB (0.47) | NPSR1CDC25BHTTPOLBHSD17B10 | |
| SCHEMBL3950722 | 0.83 | HTT (0.64) | NPSR1CDC25BHTTPOLBHSD17B10 | |
| SCHEMBL11595561 | 0.83 | POLB (0.62) | HTTPOLBHSD17B10TDP1MAPT | |
| SCHEMBL11595770 | 0.83 | HSD17B10 (0.49) | HSD17B10MYCKDM4ECA1CA2 | |
| SCHEMBL3950862 | 0.83 | CDC25B (0.63) | NPSR1CDC25BHTTPOLBHSD17B10 | |
| SCHEMBL26144894 | 0.83 | PTK2B (0.62) | NPSR1CDC25BHTTPOLBHSD17B10 | |
| SCHEMBL7952829 | 0.80 | MAPT (0.46) | POLBHSD17B10TDP1MAPTKDM4E | |
| SCHEMBL26144954 | 0.80 | NPSR1 (0.70) | NPSR1HTTPOLBPKMTDP1 | |
| SCHEMBL21962266 | 0.79 | PTK2B (0.48) | NPSR1CDC25BHTTPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1028949-B1 | CARBAMOYLPHENYLSULFONYL UREAS, METHOD FOR THEIR PRODUCTION AND THEIR APPLICATION AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER CROPSCIENCE GMBH (DE) | 2005-03-23 | — | — | EP | disclosed |
| US-6228808-B1 | BROAD SPECTRUM PRE-EMERGENCE OR POST-EMERGENCE HERBICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 2001-05-08 | — | — | US | disclosed |
| EP-1028949-A1 | CARBAMOYLPHENYLSULFONYL UREAS, METHOD FOR THEIR PRODUCTION AND THEIR APPLICATION AS HERBICIDES AND PLANT GROWTH REGULATORS | Aventis CropScience GmbH (DE) | 2000-08-23 | — | — | EP | disclosed |
| WO-1999023079-A1 | CARBAMOYLPHENYLSULFONYL UREAS, METHOD FOR THEIR PRODUCTION AND THEIR APPLICATION AS HERBICIDES AND PLANT GROWTH REGULATORS | AVENTIS CROPSCIENCE GMBH (DE) | 1999-05-14 | — | — | WO | disclosed |
| EP-0494973-A1 | COMPOUNDS USEFUL FOR MEASURING LOW LEVELS OF SULFONYLUREAS BY IMMUNOASSAY | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-07-22 | — | — | EP | disclosed |
| WO-1991004967-A1 | COMPOUNDS USEFUL FOR MEASURING LOW LEVELS OF SULFONYLUREAS BY IMMUNOASSAY | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-04-18 | — | — | WO | disclosed |