Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7953153 | 0.86 | CA1 (0.43) | MAPTKDM4ENPC1ALDH1A1HSD17B10 | |
| SCHEMBL6153148 | 0.80 | NPSR1 (0.44) | MAPTKDM4EPOLBTDP1HSD17B10 | |
| SCHEMBL11595770 | 0.79 | HSD17B10 (0.49) | KDM4EALDH1A1HSD17B10SMN1; SMN2CA1 | |
| SCHEMBL8537785 | 0.75 | ALDH1A1 (0.40) | MAPTKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL9786904 | 0.74 | CA1 (0.66) | ALDH1A1SMN1; SMN2CA1CA2MMP1 | |
| SCHEMBL6152020 | 0.74 | ACLY (0.43) | MAPTKDM4ENPC1RAB9APOLB | |
| SCHEMBL2476297 | 0.74 | ACLY (0.45) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL9201412 | 0.72 | CDK1 (0.43) | MAPTKDM4ENPC1ALDH1A1HSD17B10 | |
| SCHEMBL8661923 | 0.72 | CDK1 (0.43) | MAPTKDM4ENPC1POLBALDH1A1 | |
| SCHEMBL12998745 | 0.71 | TDP1 (0.69) | MAPTKDM4ENPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265348-B1 | Alkylidenehydrazinophenylsulfonylureas, processes for their preparation and their use as herbicides and plant growth regulators | HOECHST SCHERING AGREVO GMBH (DE) | 2001-07-24 | — | — | US | disclosed |