Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6153148 | 0.87 | NPSR1 (0.44) | POLBPKMCA1CA2MMP1 | |
| SCHEMBL7922564 | 0.82 | GAA (0.40) | MCL1CA1CA2SMN1; SMN2ALDH1A1 | |
| SCHEMBL7924891 | 0.82 | ALDH1A1 (0.36) | ACLYPOLBPDK2PDK4SMN1; SMN2 | |
| SCHEMBL11595770 | 0.77 | HSD17B10 (0.49) | ACLYCA1CA2SMN1; SMN2ALDH1A1 | |
| SCHEMBL7683864 | 0.76 | NSD2 (0.39) | SMN1; SMN2KDM4EMEN1LMNAKMT2A | |
| SCHEMBL7952829 | 0.74 | MAPT (0.46) | POLBCA1CA2MMP1MMP2 | |
| SCHEMBL6151581 | 0.72 | KDM4E (0.52) | PKMCA1CA2SMN1; SMN2ALDH1A1 | |
| SCHEMBL9786904 | 0.72 | CA1 (0.66) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL2476297 | 0.72 | ACLY (0.45) | ACLYCA1CA2MMP1MMP2 | |
| SCHEMBL7685851 | 0.72 | L3MBTL1 (0.53) | POLBALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1028949-B1 | CARBAMOYLPHENYLSULFONYL UREAS, METHOD FOR THEIR PRODUCTION AND THEIR APPLICATION AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER CROPSCIENCE GMBH (DE) | 2005-03-23 | — | — | EP | disclosed |
| US-6228808-B1 | BROAD SPECTRUM PRE-EMERGENCE OR POST-EMERGENCE HERBICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 2001-05-08 | — | — | US | disclosed |
| EP-1028949-A1 | CARBAMOYLPHENYLSULFONYL UREAS, METHOD FOR THEIR PRODUCTION AND THEIR APPLICATION AS HERBICIDES AND PLANT GROWTH REGULATORS | Aventis CropScience GmbH (DE) | 2000-08-23 | — | — | EP | disclosed |
| WO-1999023079-A1 | CARBAMOYLPHENYLSULFONYL UREAS, METHOD FOR THEIR PRODUCTION AND THEIR APPLICATION AS HERBICIDES AND PLANT GROWTH REGULATORS | AVENTIS CROPSCIENCE GMBH (DE) | 1999-05-14 | — | — | WO | disclosed |