Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11835677 | 0.84 | KDM4E (0.54) | GFERALDH1A1KDM4ETDP1PDE7A | |
| SCHEMBL9566918 | 0.83 | KDM4E (0.47) | GFERALDH1A1KDM4ETDP1PDE7A | |
| SCHEMBL11352754 | 0.82 | PKM (0.49) | ALDH1A1KDM4ETDP1SMN1; SMN2POLB | |
| SCHEMBL11346051 | 0.80 | SIRT1 (0.45) | ALDH1A1TDP1MAPTL3MBTL1MEN1 | |
| SCHEMBL1025155 | 0.77 | IDO1 (0.47) | ALDH1A1KDM4ETDP1MAPTPOLB | |
| SCHEMBL13717081 | 0.71 | FGFR1 (0.39) | ALDH1A1KDM4ETDP1SMN1; SMN2MAPT | |
| SCHEMBL1340573 | 0.70 | ALDH1A1 (0.66) | ALDH1A1KDM4ETDP1MAPTPOLB | |
| SCHEMBL11835668 | 0.70 | KDM4E (0.51) | GFERALDH1A1KDM4ETDP1PDE7A | |
| SCHEMBL713707 | 0.70 | MEN1 (0.68) | GFERALDH1A1KDM4ETDP1PDE7A | |
| SCHEMBL29869345 | 0.70 | MEN1 (0.68) | GFERALDH1A1KDM4ETDP1PDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347019-A | REACTING 4-HALONAPHTHALIC ANHYDRIDES WITH 2-AMINOTHIOPHENOLATES | CASSELLA AG (DE) | 1994-09-13 | — | — | US | claimed |
| JP-6080660-A | — | — | None | — | — | JP | disclosed |
| EP-1517316-A1 | New azo type dyes for optical data recording | CLARIANT INTERNATIONAL LTD. (CH) | 2005-03-23 | — | — | EP | disclosed |
| US-5347019-A | REACTING 4-HALONAPHTHALIC ANHYDRIDES WITH 2-AMINOTHIOPHENOLATES | CASSELLA AG (DE) | 1994-09-13 | — | — | US | disclosed |
| US-5347019-A | REACTING 4-HALONAPHTHALIC ANHYDRIDES WITH 2-AMINOTHIOPHENOLATES | CASSELLA AG (DE) | 1994-09-13 | — | — | US | disclosed |
| US-5347019-A | REACTING 4-HALONAPHTHALIC ANHYDRIDES WITH 2-AMINOTHIOPHENOLATES | CASSELLA AG (DE) | 1994-09-13 | — | — | US | disclosed |
| JP-H0680660-A | PREPARATION OF 4-(2-AMINOPHENYLTHIO)NAPHTHALIC ANHYDRIDE DERIVATIVE | CASSELLA AG | 1994-03-22 | — | — | JP | disclosed |
| US-4254109-A | INHIBIT LENS ALDOSE REDUCTASE | AYERST, MCKENNA & HARRISON INC. (CA) | 1981-03-03 | — | — | US | disclosed |