Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6153265 | 0.83 | GFER (0.42) | KDM4EALDH1A1TDP1LMNAPKM | |
| SCHEMBL11835677 | 0.80 | KDM4E (0.54) | KDM4EALDH1A1TDP1LMNARAB9A | |
| SCHEMBL11352754 | 0.77 | PKM (0.49) | KDM4EALDH1A1TDP1RAB9APKM | |
| SCHEMBL8989325 | 0.76 | NR4A1 (0.50) | KDM4EALDH1A1TDP1RAB9ARXFP1 | |
| SCHEMBL8528173 | 0.75 | SIRT1 (0.49) | ALDH1A1RAB9APKMRXFP1CDC25B | |
| SCHEMBL2032649 | 0.74 | KDM4E (0.71) | KDM4EALDH1A1TDP1LMNARAB9A | |
| SCHEMBL2804186 | 0.74 | CYP1A2 (0.48) | KDM4EALDH1A1TDP1RXFP1CDC25B | |
| Hydrochloric Acid SCHEMBL2909102 | 0.73 | KDM4E (0.69) | KDM4EALDH1A1TDP1LMNARAB9A | |
| SCHEMBL11835668 | 0.72 | KDM4E (0.51) | KDM4EALDH1A1TDP1LMNARAB9A | |
| SCHEMBL1133920 | 0.72 | G6PD (0.41) | KDM4EALDH1A1TDP1PKMRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0570778-A1 | Process for the preparation of 4-(2-aminophenylthio)-naphthalene 1-8 dicarboxylic acid anhydride derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-24 | — | — | EP | disclosed |