Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.67 |
| ▸ | CA2 | P00918 | 1/20 | 0.67 |
| ▸ | P2RX1 | P51575 | 6/20 | 0.55 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.55 |
| ▸ | TMPRSS4 | Q9NRS4 | 3/20 | 0.53 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.53 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6966672 | 0.82 | CA1 (0.72) | CA1CA2P2RX1KCNMA1TMPRSS4 | |
| SCHEMBL970982 | 0.80 | ALDH1A1 (0.65) | CA1CA2MAPTHSD17B10NPC1 | |
| 5-Chlorosalicylic Acid SCHEMBL130605 | 0.80 | CA1 (1.00) | CA1CA2P2RX1KCNMA1TMPRSS4 | |
| 5-Chlorosalicylic Acid SCHEMBL29499764 | 0.80 | CA1 (1.00) | CA1CA2P2RX1KCNMA1TMPRSS4 | |
| SCHEMBL29769239 | 0.80 | CA1 (0.69) | CA1CA2P2RX1KCNMA1TMPRSS4 | |
| SCHEMBL4955043 | 0.80 | CA1 (0.69) | CA1CA2P2RX1KCNMA1TMPRSS4 | |
| 5-Chlorosalicylic Acid SCHEMBL11158036 | 0.78 | CA1 (0.96) | CA1CA2P2RX1KCNMA1TMPRSS4 | |
| SCHEMBL218964 | 0.78 | CA1 (0.67) | CA1CA2P2RX1KCNMA1TMPRSS4 | |
| 5-Chlorosalicylic Acid SCHEMBL6855770 | 0.78 | CA1 (0.96) | CA1CA2P2RX1KCNMA1TMPRSS4 | |
| SCHEMBL6401690 | 0.78 | CA1 (0.67) | CA1CA2P2RX1KCNMA1TMPRSS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050065118-A1 | Organosulfur inhibitors of tyrosine phosphatases | METABASIS THERAPEUTICS, INC. | 2005-03-24 | — | — | US | disclosed |
| EP-1446110-A2 | ORGANOSULFUR INHIBITORS OF TYROSINE PHOSPHATASES | Structural Bioinformatics Inc. (US) | 2004-08-18 | — | — | EP | disclosed |
| WO-2003032916-A2 | ORGANOSULFUR INHIBITORS OF TYROSINE PHOSPHATASES | STRUCTURAL BIOINFORMATICS INC. (US) | 2003-04-24 | — | — | WO | disclosed |
| WO-2003007955-A2 | BIPHENYL APURINIC/APYRIMIDINIC SITE ENDONUCLEASE INHIBITORS TO TREAT CANCER | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2003-01-30 | — | — | WO | disclosed |
| US-4663353-A | Antibacterial fatty anilides | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1987-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065118-A1 | Organosulfur inhibitors of tyrosine phosphatases | PTPRS, PTPRJ, PTPRCAP | CA1 4519/4885CA2 3937/4885P2RX1 1880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.