SCHEMBL218964

SCHEMBL218964

CC(=O)c1cc(Cl)ccc1O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.67
CA2 P00918 1/20 0.67
P2RX1 P51575 8/20 0.59
TMPRSS4 Q9NRS4 5/20 0.58
P2RX4 Q99571 3/20 0.58
P2RX7 Q99572 3/20 0.58
KCNMA1 Q12791 2/20 0.55
MEN1 O00255 2/20 0.51
LMNA P02545 2/20 0.51
MAPT P10636 2/20 0.51
HPGD P15428 2/20 0.51
HTT P42858 2/20 0.51
KMT2A Q03164 2/20 0.51
KDM4E B2RXH2 1/20 0.51
PLA2G1B P04054 1/20 0.51
XBP1 P17861 1/20 0.51
ALOX12 P18054 1/20 0.51
KCNH2 Q12809 1/20 0.51
ATG4B Q9Y4P1 1/20 0.51
NPC1 O15118 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL30207997 0.98 CA1 (0.64) CA1CA2P2RX1TMPRSS4P2RX4
Hydrochloric Acid SCHEMBL11784623 0.98 CA1 (0.64) CA1CA2P2RX1TMPRSS4P2RX4
SCHEMBL9739457 0.86 CA1 (0.51) CA1CA2P2RX1TMPRSS4P2RX4
SCHEMBL17233413 0.84 ALOX5 (0.57) CA1CA2P2RX1TMPRSS4P2RX4
SCHEMBL3922668 0.83 ALDH1A1 (0.47) CA1CA2P2RX1TMPRSS4KCNMA1
SCHEMBL498707 0.83 MAOB (0.58) CA1CA2P2RX1TMPRSS4P2RX4
SCHEMBL29495428 0.83 MAOB (0.58) CA1CA2P2RX1TMPRSS4P2RX4
SCHEMBL20117002 0.82 ALDH1A1 (0.50) CA1CA2P2RX1MEN1MAPT
SCHEMBL6966672 0.82 CA1 (0.72) CA1CA2P2RX1TMPRSS4P2RX4
5-Chlorosalicylic Acid SCHEMBL28240558 0.81 CA1 (0.92) CA1CA2P2RX1TMPRSS4P2RX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 474 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116813569-B Preparation method of anticancer drug intermediate and preparation method of anticancer drug 衡阳市中心医院 2024-07-02 CN claimed
CN-116813569-A Preparation method of anticancer drug intermediate and preparation method of anticancer drug 衡阳市中心医院 2023-09-29 CN claimed
WO-2022256358-A1 PROCESS FOR PREPARING MEDICAMENTS GENENTECH, INC. (US) 2022-12-08 WO claimed
CN-115259150-A Production process of biomass-based hard carbon material based on high-temperature sintering modification 江苏智纬电子科技有限公司 2022-11-01 CN claimed
CN-114751870-A 2- (isoxazole-5-yl) phenyl-3, 4-dihydroxy benzoate and derivative thereof, and synthesis method and application thereof 贵州医科大学 2022-07-15 CN claimed
CN-111996222-A Method for preparing drug intermediate (R) -2- (aminoethyl) -4-chlorophenol by adopting enzyme mutation technology 赣江新区生鸿企业管理中心(有限合伙) 2020-11-27 CN claimed
CN-107698452-B Synthetic method of 3-amino-2-hydroxyacetophenone 黑龙江鑫创生物科技开发有限公司 2020-06-02 CN claimed
US-20080254130-A1 Skin Antiaging & Brightening via Multi-function Treatment of Enzyme Dysfunction BIODERM RESEARCH (US) 2008-10-16 US claimed
US-20060269494-A1 New Ubiquitin-Proteasome Regulating Compounds and Their Application in Cosmetic and Pharmaceutical Formulations GUPTA SHYAM K 2006-11-30 US claimed
US-20060110415-A1 Topical Delivery System for Cosmetic and Pharmaceutical Agents BIODERM RESEARCH (US) 2006-05-25 US claimed
US-20060074108-A1 Matrix metalloprotease (MMP) inhibitors and their application in cosmetic and pharmaceutical composition BIODERM RESEARCH (US) 2006-04-06 US claimed
US-20050271608-A1 Skin whitening compositions based on hydroxyaryl alkyl ketones and their isosteric derivatives GUPTA SHYAM K 2005-12-08 US claimed
JP-9040619-A None JP disclosed
EP-3558298-B1 ANTIDIABETIC SPIROCHROMAN COMPOUNDS MERCK SHARP & DOHME LLC (US) 2026-03-11 EP disclosed
EP-3974434-B1 MACROLIDE DERIVATIVES, PREPARATION METHOD AND APPLICATION THEREOF ZHEJIANG HISUN PHARM CO LTD (CN) 2025-11-19 EP disclosed
US-12410191-B2 Macrolide derivatives, preparation method and application thereof ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) 2025-09-09 US disclosed
US-4002423-A Benzofuran derivatives process for their preparation and their use as optical brighteners HOECHST AKTIENGESELLSCHAFT (DT) 1977-01-11 US disclosed
US-3994902-A Certain 1,2-diphenyl-1,2,3,4-tetrahydroquinoline compounds STERLING DRUG INC. (US) 1976-11-30 US disclosed
US-3956369-A N-β-(2-acetyl-4-chlorophenoxy)-ethyl-N,N-dimethyl-N-benzyl-ammonium-p-chlorobenzene sulphonate, method for preparing same and medicinal preparation based thereon OZERETSKOVSKAYA NATALIA NIKOLA 1976-05-11 US disclosed
US-3956369-A N-β-(2-acetyl-4-chlorophenoxy)-ethyl-N,N-dimethyl-N-benzyl-ammonium-p-chlorobenzene sulphonate, method for preparing same and medicinal preparation based thereon OZERETSKOVSKAYA NATALIA NIKOLA 1976-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12410191-B2 Macrolide derivatives, preparation method and application thereof ROS1, IRAK1, IRAK2 CA1 4881/4885CA2 4700/4885P2RX1 4203/4885
US-20080254130-A1 Skin Antiaging & Brightening via Multi-function Treatment of Enzyme Dysfunction PSMB1, PLOD3, CUTA CA1 4867/4885CA2 4627/4885P2RX1 4332/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.