Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | TP53 | P04637 | 3/20 | 0.65 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.52 |
| ▸ | FEN1 | P39748 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
| ▸ | TYK2 | P29597 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | FLT4 | P35916 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL350009 | 0.82 | SMN1; SMN2 (0.65) | ALDH1A1TP53ERCC5FEN1TSHR | |
| SCHEMBL8160214 | 0.81 | ALDH1A1 (0.71) | ALDH1A1TP53ERCC5FEN1TSHR | |
| SCHEMBL6153483 | 0.80 | CA1 (0.67) | TP53TSHRSMN1; SMN2LMNAALOX15 | |
| SCHEMBL224469 | 0.79 | ALDH1A1 (1.00) | ALDH1A1TP53ERCC5FEN1TSHR | |
| SCHEMBL10541315 | 0.79 | ALDH1A1 (0.68) | ALDH1A1TP53ERCC5FEN1TSHR | |
| SCHEMBL699001 | 0.79 | ALDH1A1 (0.68) | ALDH1A1TP53ERCC5FEN1TSHR | |
| SCHEMBL5667181 | 0.79 | ALDH1A1 (0.68) | ALDH1A1TP53ERCC5FEN1TSHR | |
| SCHEMBL3038177 | 0.77 | ALDH1A1 (0.65) | ALDH1A1TP53ERCC5FEN1TSHR | |
| SCHEMBL9586276 | 0.77 | ALDH1A1 (0.65) | ALDH1A1TP53ERCC5FEN1TSHR | |
| Hydrochloric Acid SCHEMBL699002 | 0.77 | ALDH1A1 (0.95) | ALDH1A1TP53ERCC5FEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110009463-A1 | GERANYLGERANYL TRANSFERASE INHIBITORS AND METHODS OF MAKING AND USING THE SAME | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-01-13 | — | — | US | claimed |
| WO-2009051772-A1 | GERANYLGERANYL TRANSFERASE INHIBITORS AND METHODS OF MAKING AND USING THE SAME | DUKE UNIVERSITY (US) | 2009-04-23 | — | — | WO | claimed |
| US-4159265-A | Phenylazopyrazolo dyestuffs including disulfimide substituent | BAYER AKTIENGESELLSCHAFT (DE) | 1979-06-26 | — | — | US | claimed |
| US-8404036-B2 | Water-soluble near-infrared absorbing coloring matters and aqueous inks containing same | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2013-03-26 | — | — | US | disclosed |
| US-20110123784-A1 | WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2011-05-26 | — | — | US | disclosed |
| US-20110009463-A1 | GERANYLGERANYL TRANSFERASE INHIBITORS AND METHODS OF MAKING AND USING THE SAME | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-01-13 | — | — | US | disclosed |
| WO-2009051772-A1 | GERANYLGERANYL TRANSFERASE INHIBITORS AND METHODS OF MAKING AND USING THE SAME | DUKE UNIVERSITY (US) | 2009-04-23 | — | — | WO | disclosed |
| US-4243584-A | Monoazo dyestuffs containing diazo component substituted by disulfimide and trifluoromethyl groups | BAYER AKTIENGESELLSCHAFT (DE) | 1981-01-06 | — | — | US | disclosed |
| US-4159265-A | Phenylazopyrazolo dyestuffs including disulfimide substituent | BAYER AKTIENGESELLSCHAFT (DE) | 1979-06-26 | — | — | US | disclosed |
| US-4022763-A | Sulfaphenyl-azo-phenyl-azo-aminophenyl dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-10 | — | — | US | disclosed |
| US-3978039-A | POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110123784-A1 | WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME | IK, RB1, COL1A1 | ALDH1A1 218/4885TP53 276/4885ERCC5 2330/4885 |
| US-20110009463-A1 | GERANYLGERANYL TRANSFERASE INHIBITORS AND METHODS OF MAKING AND USING THE SAME | FNTA, GGPS1, PTAR1 | ALDH1A1 2906/4885TP53 2393/4885ERCC5 3530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.