Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.56 |
| ▸ | DRD4 | P21917 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.56 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.56 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6157025 | 0.99 | LTA4H (0.65) | LTA4HGAAKCNH2SIGMAR1DRD4 | |
| SCHEMBL6154433 | 0.95 | LTA4H (0.61) | LTA4HGAAKCNH2SIGMAR1DRD4 | |
| SCHEMBL6156841 | 0.93 | GAA (0.59) | LTA4HGAAKCNH2SIGMAR1DRD4 | |
| SCHEMBL4229314 | 0.90 | LTA4H (0.80) | LTA4HKCNH2SIGMAR1DRD4KMT2A | |
| SCHEMBL6153437 | 0.85 | ROCK2 (0.60) | LTA4HGAAKCNH2DRD4DRD2 | |
| SCHEMBL8070227 | 0.85 | ALDH1A1 (0.68) | LTA4HGAASIGMAR1KMT2AMCHR1 | |
| SCHEMBL23805141 | 0.84 | KMT2A (0.66) | LTA4HGAASIGMAR1DRD4KMT2A | |
| SCHEMBL6154132 | 0.83 | POLB (0.56) | LTA4HGAAKCNH2SIGMAR1DRD4 | |
| SCHEMBL918426 | 0.83 | KDM4E (0.66) | LTA4HGAASIGMAR1DRD4KMT2A | |
| SCHEMBL6153398 | 0.82 | GAA (0.70) | GAAKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050182040-A1 | Benzamide derivatives | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2005-08-18 | — | — | US | disclosed |
| EP-1500643-A1 | BENZAMIDE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2005-01-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182040-A1 | Benzamide derivatives | ROCK1, ROCK2, NHERF1 | LTA4H 1043/4885GAA 2875/4885KCNH2 118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.