Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KMO | O15229 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6153319 | 0.85 | KMO (0.60) | KMT2AMEN1ALDH1A1KMOLMNA | |
| SCHEMBL5183927 | 0.81 | ALDH1A1 (0.56) | KMT2AMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL1067933 | 0.81 | TSHR (0.50) | KMT2AMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL10539201 | 0.80 | KMT2A (0.62) | KMT2AMEN1ALDH1A1KMOCES2 | |
| SCHEMBL18300806 | 0.79 | KMT2A (0.60) | KMT2AMEN1ALDH1A1KMOCES2 | |
| SCHEMBL22347378 | 0.79 | ALDH1A1 (0.58) | KMT2AMEN1ALDH1A1KMOLMNA | |
| SCHEMBL5756510 | 0.79 | CES2 (0.60) | KMT2AMEN1ALDH1A1KMOCES2 | |
| SCHEMBL5869531 | 0.78 | MAPT (0.62) | KMT2AMEN1ALDH1A1KMOLMNA | |
| SCHEMBL2083613 | 0.78 | SRC (0.58) | KMT2AMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL17788611 | 0.78 | ADRB2 (0.58) | KMT2AMEN1ALDH1A1KMOLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499603-A1 | ANTIVIRAL LACTONE-UREAS | Bayer Aktiengesellschaft (DE) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003089421-A1 | ANTIVIRAL LACTONE-UREAS | BAYER HEALTHCARE AG (DE) | 2003-10-30 | — | — | WO | disclosed |