Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.63 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.53 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ALPL | P05186 | 1/20 | 0.51 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.50 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | JAK3 | P52333 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6153790 | 0.88 | KDM4E (0.54) | MKNK1MKNK2KDM4ERAB9ANPC1 | |
| SCHEMBL6155111 | 0.84 | MKNK1 (0.51) | MKNK1MKNK2RAB9ASMN1; SMN2MAPK8 | |
| SCHEMBL6154777 | 0.84 | MAPK9 (0.59) | MKNK1MKNK2RAB9ANPC1MAPT | |
| SCHEMBL3123583 | 0.81 | L3MBTL1 (0.60) | MKNK1MKNK2KDM4EMAPTTSHR | |
| SCHEMBL17774917 | 0.79 | JAK2 (0.52) | MKNK1MKNK2RAB9ANPC1LMNA | |
| SCHEMBL6154065 | 0.77 | JAK2 (0.58) | MKNK1MKNK2KDM4ERAB9ANPC1 | |
| SCHEMBL9409078 | 0.75 | KDM4E (0.53) | MKNK1MKNK2KDM4ERAB9ANPC1 | |
| SCHEMBL9409081 | 0.75 | JAK2 (0.56) | MKNK1MKNK2KDM4ERAB9ANPC1 | |
| SCHEMBL2908801 | 0.74 | MKNK1 (0.50) | MKNK1MKNK2KDM4ERAB9ANPC1 | |
| SCHEMBL5915825 | 0.74 | RAB9A (0.48) | KDM4ERAB9ANPC1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050182040-A1 | Benzamide derivatives | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2005-08-18 | — | — | US | disclosed |
| EP-1500643-A1 | BENZAMIDE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2005-01-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182040-A1 | Benzamide derivatives | ROCK1, ROCK2, NHERF1 | MKNK1 2457/4885MKNK2 2644/4885KDM4E 2017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.