Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155476 | 0.81 | CYP1A2 (0.46) | L3MBTL1MEN1NR1I2LMNACHRM2 | |
| SCHEMBL10383939 | 0.77 | LMNA (0.37) | PPARGMEN1NR1I2LMNACHRM2 | |
| SCHEMBL5549224 | 0.76 | ALDH1A1 (0.44) | L3MBTL1MEN1LMNAMAPTKMT2A | |
| SCHEMBL9488066 | 0.73 | PPARG (0.37) | PPARGL3MBTL1MEN1NR1I2LMNA | |
| SCHEMBL9488200 | 0.72 | LMNA (0.42) | PPARGMEN1NR1I2LMNACHRM2 | |
| SCHEMBL7897440 | 0.72 | ALDH1A1 (0.37) | L3MBTL1MEN1LMNAMAPTKMT2A | |
| SCHEMBL6155219 | 0.71 | ALDH1A1 (0.39) | L3MBTL1MEN1LMNAMAPTKMT2A | |
| SCHEMBL7091621 | 0.70 | CCNB2 (0.50) | L3MBTL1MEN1LMNACYP3A4MAPT | |
| SCHEMBL10384182 | 0.69 | PPARG (0.40) | PPARGMEN1NR1I2LMNACHRM2 | |
| SCHEMBL9145900 | 0.69 | LTA4H (0.49) | NR1I2LMNACHRM2CYP3A4ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025079-B1 | $g(a)-ARYL-$i(N)-ALKYLNITRONES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | RENOVIS INC (US) | 2005-02-02 | — | — | EP | claimed |