Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MELK | Q14680 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 6/20 | 0.34 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.33 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.33 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6153884 | 1.00 | MELK (0.38) | MELKNSD2PGRSUV39H2CYP2D6 | |
| SCHEMBL6154049 | 0.84 | IMPDH2 (0.41) | MELKNSD2SUV39H2ALDH1A1AR | |
| SCHEMBL6154051 | 0.84 | IMPDH2 (0.41) | MELKNSD2SUV39H2ALDH1A1AR | |
| SCHEMBL6153395 | 0.84 | SUV39H2 (0.44) | NSD2SUV39H2ALDH1A1KDM4EGAA | |
| SCHEMBL6153396 | 0.84 | SUV39H2 (0.44) | NSD2SUV39H2ALDH1A1KDM4EGAA | |
| SCHEMBL6154446 | 0.84 | SUV39H2 (0.44) | NSD2SUV39H2ALDH1A1KDM4EGAA | |
| SCHEMBL6155712 | 0.82 | MELK (0.48) | MELKPGRALDH1A1ARHTT | |
| SCHEMBL6155718 | 0.82 | MELK (0.48) | MELKPGRALDH1A1ARHTT | |
| SCHEMBL22692284 | 0.76 | PGR (0.53) | PGRARGPR119 | |
| SCHEMBL6153762 | 0.76 | CDK7 (0.41) | MELKPGRALDH1A1ARKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050182040-A1 | Benzamide derivatives | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2005-08-18 | — | — | US | disclosed |
| EP-1500643-A1 | BENZAMIDE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2005-01-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182040-A1 | Benzamide derivatives | ROCK1, ROCK2, NHERF1 | MELK 2442/4885NSD2 2185/4885PGR 1690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.