Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 4/20 | 0.45 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.45 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 3/20 | 0.42 |
| ▸ | MMP3 | P08254 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10778667 | 0.86 | KMT2A (0.43) | LNPEPERAP2ERAP1ACEMMP1 | |
| SCHEMBL11537085 | 0.80 | CPB2 (0.47) | — | |
| SCHEMBL11537079 | 0.80 | CPB2 (0.47) | — | |
| SCHEMBL5553739 | 0.80 | ECE1 (0.46) | LNPEPPRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL3369068 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2ANPEPCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL5349213 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2ANPEPCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL5348541 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2ANPEPCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL9022605 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2ANPEPCHRNB2CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL5548318 | 0.79 | ECE1 (0.46) | LNPEPPRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL6237696 | 0.75 | ACE (0.58) | LNPEPERAP2ERAP1ACESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513868-A1 | PROCESS FOR THE PRODUCTION OF LISINOPRIL | EOS Eczacibasi Ozgun Kimyasal Urunler Sanayi Ve Ti Caret A.S. (TR) | 2005-03-16 | — | — | EP | disclosed |
| WO-2004000874-A1 | PROCESS FOR THE PRODUCTION OF LISINOPRIL | EOS ECZACIBASI OZGUN KIMYASAL URUNLER SANYI VE TI CARET A.S. (TR) | 2003-12-31 | — | — | WO | disclosed |