Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | CTSG | P08311 | 2/20 | 0.35 |
| ▸ | CMA1 | P23946 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6154070 | 0.86 | LNPEP (0.45) | LNPEPACEERAP2ERAP1TLR2 | |
| SCHEMBL3368639 | 0.79 | KMT2A (0.43) | KMT2AMEN1NPC1POLBNPSR1 | |
| SCHEMBL9856515 | 0.79 | KMT2A (0.43) | KMT2AMEN1NPC1POLBNPSR1 | |
| SCHEMBL11537079 | 0.79 | CPB2 (0.47) | KMT2APOLB | |
| SCHEMBL11537085 | 0.79 | CPB2 (0.47) | KMT2APOLB | |
| SCHEMBL7864695 | 0.74 | ITGB3 (0.50) | LNPEPACEERAP2ERAP1CTSG | |
| SCHEMBL5553739 | 0.74 | ECE1 (0.46) | LNPEPTLR2 | |
| Hydrochloric Acid SCHEMBL5548318 | 0.73 | ECE1 (0.46) | LNPEPTLR2 | |
| SCHEMBL1657139 | 0.71 | CTSK (0.43) | LNPEPERAP2ERAP1 | |
| SCHEMBL9856677 | 0.71 | KMT2A (0.44) | KMT2AMEN1NPC1POLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239062-A2 | N2-(1-carboxy-3-oxo-3-phenylpropyl)-L-Lysine compounds and their derivatives | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1987-09-30 | — | — | EP | disclosed |