Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.53 |
| ▸ | TLR2 | O60603 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | PTAFR | P25105 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | FES | P07332 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | MARK3 | P27448 | 1/20 | 0.43 |
| ▸ | TYK2 | P29597 | 1/20 | 0.43 |
| ▸ | FLT4 | P35916 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6157548 | 0.88 | FAAH (0.56) | FAAHTRPV1CTSKCYP3A4FES | |
| SCHEMBL6156048 | 0.86 | TLR2 (0.50) | TLR2CTSKHDAC2HDAC8HDAC6 | |
| SCHEMBL6157034 | 0.82 | TDP1 (0.54) | FAAHTLR2TDP1L3MBTL1TRPV1 | |
| SCHEMBL22861334 | 0.80 | HDAC8 (0.51) | L3MBTL1PTAFRHDAC2HDAC8HDAC6 | |
| SCHEMBL30444565 | 0.78 | FAAH (0.67) | FAAHTDP1L3MBTL1TRPV1PTAFR | |
| SCHEMBL2186612 | 0.78 | FAAH (0.67) | FAAHTDP1L3MBTL1TRPV1PTAFR | |
| SCHEMBL6155335 | 0.78 | TLR2 (0.52) | TLR2TDP1CTSKCYP3A4NPC1 | |
| SCHEMBL2755877 | 0.77 | HDAC2 (0.56) | FAAHHDAC2HDAC8HDAC6CYP3A4 | |
| SCHEMBL23868225 | 0.77 | FAAH (0.55) | FAAHTLR2TDP1L3MBTL1TRPV1 | |
| SCHEMBL6155149 | 0.76 | LMNA (0.52) | FAAHCTSKSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499326-A1 | OXOLIDE ANTIBACTERIALS | Abbott Laboratories (US) | 2005-01-26 | — | — | EP | claimed |
| WO-2003090760-A1 | OXOLIDE ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2003-11-06 | — | — | WO | claimed |
| EP-1499326-A1 | OXOLIDE ANTIBACTERIALS | Abbott Laboratories (US) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003090760-A1 | OXOLIDE ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2003-11-06 | — | — | WO | disclosed |