Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 3/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155149 | 0.87 | LMNA (0.52) | NAAASMN1; SMN2LMNAHTTCTSK | |
| SCHEMBL6154341 | 0.86 | FAAH (0.53) | TLR2SMN1; SMN2RAB9ANPC1CTSK | |
| SCHEMBL6155335 | 0.80 | TLR2 (0.52) | TLR2SMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL22281735 | 0.78 | SMN1; SMN2 (0.52) | SMN1; SMN2RAB9ANPC1LMNAHTT | |
| SCHEMBL6154864 | 0.78 | EPHX1 (0.52) | CTSKMGLL | |
| SCHEMBL20543214 | 0.76 | HSD17B10 (0.63) | SMN1; SMN2RAB9ANPC1LMNAHDAC2 | |
| SCHEMBL2189223 | 0.76 | HSD17B10 (0.63) | SMN1; SMN2RAB9ANPC1LMNAHDAC2 | |
| SCHEMBL6157548 | 0.76 | FAAH (0.56) | LMNACTSKTSHRMAPTMAPK1 | |
| SCHEMBL7125935 | 0.75 | EPHX1 (0.49) | NAAACTSK | |
| Hydrochloric Acid SCHEMBL20543011 | 0.75 | HSD17B10 (0.61) | SMN1; SMN2RAB9ANPC1LMNAHDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499326-A1 | OXOLIDE ANTIBACTERIALS | Abbott Laboratories (US) | 2005-01-26 | — | — | EP | claimed |
| WO-2003090760-A1 | OXOLIDE ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2003-11-06 | — | — | WO | claimed |
| EP-1499326-A1 | OXOLIDE ANTIBACTERIALS | Abbott Laboratories (US) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003090760-A1 | OXOLIDE ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2003-11-06 | — | — | WO | disclosed |