Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 13/20 | 0.48 |
| ▸ | MKNK1 | Q9BUB5 | 5/20 | 0.45 |
| ▸ | MKNK2 | Q9HBH9 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6153679 | 0.86 | HTR4 (0.48) | MKNK1MKNK2 | |
| SCHEMBL6153513 | 0.83 | SYK (0.46) | IRAK4MKNK1MKNK2 | |
| SCHEMBL6154140 | 0.82 | HTR4 (0.45) | — | |
| SCHEMBL6155360 | 0.81 | MAPT (0.46) | MKNK1MKNK2 | |
| SCHEMBL6153310 | 0.81 | EPHX1 (0.48) | IRAK4MKNK1MKNK2 | |
| SCHEMBL6155049 | 0.80 | FLT3 (0.44) | — | |
| SCHEMBL6153421 | 0.78 | AURKA (0.45) | — | |
| SCHEMBL6154103 | 0.78 | MCHR1 (0.51) | — | |
| SCHEMBL6156769 | 0.77 | ROCK2 (0.47) | — | |
| SCHEMBL6153710 | 0.77 | RPS6KB1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050182040-A1 | Benzamide derivatives | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2005-08-18 | — | — | US | disclosed |
| EP-1500643-A1 | BENZAMIDE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2005-01-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182040-A1 | Benzamide derivatives | ROCK1, ROCK2, NHERF1 | IRAK4 3240/4885MKNK1 2457/4885MKNK2 2644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.