Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.61 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.61 |
| ▸ | CCR2 | P41597 | 1/20 | 0.61 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | SCN4A | P35499 | 2/20 | 0.54 |
| ▸ | BCHE | P06276 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6154047 | 0.86 | LTA4H (0.67) | ROCK2ROCK1GAALTA4H | |
| SCHEMBL1553646 | 0.84 | CYP3A4 (0.69) | ROCK2ROCK1CCR2DRD3CYP3A4 | |
| SCHEMBL6153437 | 0.82 | ROCK2 (0.60) | ROCK2ROCK1CCR2GAAALDH1A1 | |
| SCHEMBL4792481 | 0.81 | KDM4E (0.63) | ROCK2ROCK1CCR2GAACYP3A4 | |
| SCHEMBL4792478 | 0.81 | KDM4E (0.63) | ROCK2ROCK1CCR2GAACYP3A4 | |
| SCHEMBL2444402 | 0.79 | GAA (0.77) | GAACYP3A4CYP2C9CYP1A2KDM4E | |
| SCHEMBL3314498 | 0.79 | GAA (0.77) | GAACYP3A4CYP2C9CYP1A2KDM4E | |
| SCHEMBL5870879 | 0.78 | DRD3 (0.77) | ROCK2ROCK1CCR2DRD3GAA | |
| SCHEMBL6154433 | 0.77 | LTA4H (0.61) | ROCK2ROCK1CCR2DRD3GAA | |
| SCHEMBL6156841 | 0.77 | GAA (0.59) | ROCK2ROCK1CCR2GAABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050182040-A1 | Benzamide derivatives | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2005-08-18 | — | — | US | disclosed |
| EP-1500643-A1 | BENZAMIDE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2005-01-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182040-A1 | Benzamide derivatives | ROCK1, ROCK2, NHERF1 | ROCK2 2/4885ROCK1 1/4885CCR2 1487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.