Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.59 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.59 |
| ▸ | CCR3 | P51677 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4172844 | 0.86 | LTA4H (0.65) | LTA4HROCK2ROCK1CCR3 | |
| SCHEMBL6154448 | 0.86 | ROCK2 (0.61) | LTA4HGAAROCK2ROCK1 | |
| SCHEMBL6154064 | 0.83 | GAA (0.70) | GAA | |
| SCHEMBL6153555 | 0.82 | LTA4H (0.66) | LTA4HGAAROCK2ROCK1 | |
| SCHEMBL1554194 | 0.82 | TDP1 (0.61) | LTA4HROCK2ROCK1CCR3 | |
| Hydrochloric Acid SCHEMBL6157025 | 0.81 | LTA4H (0.65) | LTA4HGAAROCK2ROCK1 | |
| SCHEMBL6153398 | 0.81 | GAA (0.70) | GAA | |
| SCHEMBL28410341 | 0.79 | MEN1 (0.61) | GAA | |
| SCHEMBL6154433 | 0.79 | LTA4H (0.61) | LTA4HGAAROCK2ROCK1 | |
| SCHEMBL25845705 | 0.78 | NAMPT (0.62) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050182040-A1 | Benzamide derivatives | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2005-08-18 | — | — | US | disclosed |
| EP-1500643-A1 | BENZAMIDE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2005-01-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182040-A1 | Benzamide derivatives | ROCK1, ROCK2, NHERF1 | LTA4H 1043/4885GAA 2875/4885ROCK2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.