Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 3/20 | 0.43 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | CTSG | P08311 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6154691 | 1.00 | L3MBTL1 (0.46) | L3MBTL1MMENPSR1NPC1RAB9A | |
| SCHEMBL6154695 | 1.00 | L3MBTL1 (0.46) | L3MBTL1MMENPSR1NPC1RAB9A | |
| SCHEMBL6155034 | 0.87 | L3MBTL1 (0.48) | L3MBTL1MMENPSR1NPC1RAB9A | |
| SCHEMBL6155028 | 0.87 | L3MBTL1 (0.48) | L3MBTL1MMENPSR1NPC1RAB9A | |
| SCHEMBL6154048 | 0.87 | L3MBTL1 (0.48) | L3MBTL1MMENPSR1NPC1RAB9A | |
| SCHEMBL6154220 | 0.87 | L3MBTL1 (0.48) | L3MBTL1MMENPSR1NPC1RAB9A | |
| SCHEMBL6154054 | 0.87 | L3MBTL1 (0.48) | L3MBTL1MMENPSR1NPC1RAB9A | |
| SCHEMBL6947426 | 0.87 | L3MBTL1 (0.48) | L3MBTL1MMENPSR1NPC1RAB9A | |
| SCHEMBL20450191 | 0.80 | L3MBTL1 (0.46) | L3MBTL1MMENPSR1NPC1RAB9A | |
| SCHEMBL1696507 | 0.79 | MME (0.67) | L3MBTL1MMENPSR1FPR2NAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1078919-B1 | SYNTHESIS OF ALPHA-AMINO-ALPHA',ALPHA'-DIHALOKETONES AND PROCESS FOR THE PREPARATION OF BETA)-AMINO ACID DERIVATIVES BY THE USE OF THE SAME | KANEKA CORP (JP) | 2005-12-07 | — | — | EP | disclosed |
| US-20030158436-A1 | Synthesis of alpha--amino-alpha, alpha'- dihaloketones and process for the preparation of beta--amino acid derivatives by the use of the same | KANEKA CORPORATION | 2003-08-21 | — | — | US | disclosed |
| US-6573399-B1 | Reacting an alpha -amino acid ester derivative with a base and a dihalomethane | KANEKA CORPORATION (JP) | 2003-06-03 | — | — | US | disclosed |
| EP-1078919-A1 | SYNTHESIS OF $g(a)-AMINO-$g(a)',$g(a)'-DIHALOKETONES AND PROCESS FOR THE PREPARATION OF $g(b)-AMINO ACID DERIVATIVES BY THE USE OF THE SAME | KANEKA CORPORATION (JP) | 2001-02-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030158436-A1 | Synthesis of alpha--amino-alpha, alpha'- dihaloketones and process for the preparation of beta--amino acid derivatives by the use of the same | AADAT, BCAT1, AASDHPPT | L3MBTL1 394/4885MME 783/4885NPSR1 2672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.