Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | ATM | Q13315 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6665515 | 0.72 | MAPT (0.52) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL12453557 | 0.71 | ALDH1A1 (0.57) | ALDH1A1LMNAALOX12HPGDKMT2A | |
| SCHEMBL3469805 | 0.70 | RAB9A (0.63) | ALDH1A1LMNAHPGDKMT2AMEN1 | |
| SCHEMBL2335088 | 0.70 | RAB9A (0.63) | ALDH1A1LMNAHPGDKMT2AMEN1 | |
| SCHEMBL6153460 | 0.70 | RRM1 (0.56) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL13673579 | 0.69 | RAB9A (0.61) | ALDH1A1LMNAHPGDKMT2AMEN1 | |
| SCHEMBL13673581 | 0.69 | RAB9A (0.61) | ALDH1A1LMNAHPGDKMT2AMEN1 | |
| SCHEMBL6154622 | 0.68 | SMN1; SMN2 (0.55) | ALDH1A1LMNAALOX12KMT2AMEN1 | |
| SCHEMBL12746344 | 0.68 | NPC1 (1.00) | LMNAKMT2AMEN1MAPTRAB9A | |
| SCHEMBL4555003 | 0.68 | IDO1 (0.78) | ALDH1A1LMNAALOX12HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050065118-A1 | Organosulfur inhibitors of tyrosine phosphatases | METABASIS THERAPEUTICS, INC. | 2005-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065118-A1 | Organosulfur inhibitors of tyrosine phosphatases | PTPRS, PTPRJ, PTPRCAP | ALDH1A1 961/4885LMNA 4884/4885ALOX12 3916/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.