Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 7/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.46 |
| ▸ | RELA | Q04206 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.38 |
| ▸ | BRD2 | P25440 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6154971 | 0.86 | PLA2G2A (0.57) | MRGPRX4SMN1; SMN2TP53PKMNFKB1 | |
| SCHEMBL16034423 | 0.86 | PLA2G2A (0.53) | MRGPRX4SMN1; SMN2TP53PKMNFKB1 | |
| SCHEMBL6881489 | 0.86 | KDM4E (0.41) | MRGPRX4SMN1; SMN2KMT2AMEN1RAB9A | |
| SCHEMBL4879634 | 0.79 | KDM4E (0.46) | MRGPRX4SMN1; SMN2TP53PKMNFKB1 | |
| SCHEMBL6155258 | 0.78 | ACHE (0.32) | SMN1; SMN2RAB9A | |
| SCHEMBL6157821 | 0.75 | ALDH1A1 (0.31) | SMN1; SMN2RAB9A | |
| SCHEMBL6156178 | 0.75 | ALDH1A1 (0.36) | SMN1; SMN2RAB9ATDP1NPC1 | |
| SCHEMBL25236496 | 0.74 | SMN1; SMN2 (0.53) | MRGPRX4SMN1; SMN2TP53PKMNFKB1 | |
| SCHEMBL31359135 | 0.74 | SMN1; SMN2 (0.53) | MRGPRX4SMN1; SMN2TP53PKMNFKB1 | |
| SCHEMBL4876609 | 0.74 | RAB9A (0.45) | MRGPRX4SMN1; SMN2TP53PKMNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |