SCHEMBL6155263

SCHEMBL6155263

CCOCOc1cc(CO)cc(C(OC)OCC)c1

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6157824 0.86 FFAR1 (0.32) FFAR1
SCHEMBL6155467 0.79 PLA2G2A (0.40) FFAR1
SCHEMBL6156485 0.79 CYP4F2 (0.36)
SCHEMBL16035693 0.79 CYP4F2 (0.36)
SCHEMBL6881492 0.78 MAPT (0.36) FFAR1
SCHEMBL6156181 0.77 BCHE (0.32)
SCHEMBL6155258 0.72 ACHE (0.32)
SCHEMBL6155603 0.72 FFAR1 (0.39) FFAR1
SCHEMBL643648 0.69 FYN (0.40) FFAR1
SCHEMBL16958938 0.68 PTGS2 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1124779-B1 VITAMIN D ANALOGUES GALDERMA RES & DEV (FR) 2005-02-02 EP disclosed
US-6689922-B1 BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) 2004-02-10 US disclosed
EP-1124779-A1 VITAMIN D ANALOGUES Galderma Research & Development, S.N.C. (FR) 2001-08-22 EP disclosed
WO-2000026167-A1 VITAMIN D ANALOGUES GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) 2000-05-11 WO disclosed