Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16035693 | 0.91 | CYP4F2 (0.36) | ACHEDAOCYP4F2CYP4A11GPBAR1 | |
| SCHEMBL6156485 | 0.88 | CYP4F2 (0.36) | ACHEDAOCYP4F2CYP4A11GPBAR1 | |
| SCHEMBL6157821 | 0.83 | ALDH1A1 (0.31) | ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL19535070 | 0.80 | ACHE (0.44) | ACHEDAOCYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL6155465 | 0.78 | MRGPRX4 (0.46) | RAB9ASMN1; SMN2 | |
| SCHEMBL16033984 | 0.77 | NQO1 (0.34) | ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL6156178 | 0.76 | ALDH1A1 (0.36) | ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL6881489 | 0.76 | KDM4E (0.41) | ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL5236102 | 0.76 | NQO1 (0.46) | ACHEDAOCYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL23907102 | 0.74 | LTA4H (0.36) | CYP4F2CYP4A11ALDH1A1SMN1; SMN2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |