Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ESR1 | P03372 | 8/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | AR | P10275 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11671106 | 0.83 | TP53 (0.54) | TDP1TP53PDE10AMAPTESR1 | |
| SCHEMBL1598733 | 0.81 | TSHR (0.48) | TDP1MAPTALDH1A1TSHRHSD17B10 | |
| SCHEMBL25540950 | 0.80 | ALDH1A1 (0.59) | TDP1MAPTALDH1A1TSHRHSD17B10 | |
| SCHEMBL15894584 | 0.79 | ESR1 (0.47) | TDP1TP53PDE10AMAPTESR1 | |
| SCHEMBL346399 | 0.77 | ALDH1A1 (0.53) | TDP1TP53MAPTALDH1A1TSHR | |
| SCHEMBL3992952 | 0.77 | HSP90AA1 (0.49) | TDP1TP53PDE10AMAPTESR1 | |
| SCHEMBL9230516 | 0.76 | APP (0.50) | TDP1TP53MAPTALDH1A1TSHR | |
| SCHEMBL10485810 | 0.76 | S100B (0.60) | TDP1TP53MAPTESR1ALDH1A1 | |
| SCHEMBL30966777 | 0.75 | ALDH1A1 (0.50) | TDP1TP53MAPTALDH1A1TSHR | |
| SCHEMBL13990194 | 0.75 | ALDH1A1 (0.50) | TDP1TP53MAPTALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112194767-B | Benzoxazine resin containing zwitter-ion group and preparation method and application thereof | 山东大学 | 2021-06-29 | — | — | CN | claimed |
| US-5691122-A | REDOX SYSTEMS, COCATALYSTS, REHALOGENATION | EASTMAN KODAK COMPANY (US) | 1997-11-25 | — | — | US | claimed |
| US-5656416-A | REVERSE REDOX COUPLE; SYNERGISTIC BLEACHING | EASTMAN KODAK COMPANY (US) | 1997-08-12 | — | — | US | claimed |
| US-9145410-B2 | Pyrazolopyridines and analogs thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-09-29 | — | — | US | disclosed |
| US-8263657-B2 | Blocking neurokinins; using a benzene compound containing hydroxy or acetoxy group; antiinflammatory agents | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2012-09-11 | — | — | US | disclosed |
| US-20120121651-A1 | PYRAZOLOPYRIDINES AND ANALOGS THEREOF | 3M INNOVATIVE PROPERTIES COMPANY | 2012-05-17 | — | — | US | disclosed |
| EP-1352650-B1 | INHIBITORS AGAINST THE PRODUCTION AND RELEASE OF INFLAMMATORY CYTOKINES | INST MED MOLECULAR DESIGN INC (JP) | 2012-03-07 | — | — | EP | disclosed |
| US-8097759-B2 | Inflammatory cytokine release inhibitor | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2012-01-17 | — | — | US | disclosed |
| US-7879849-B2 | such as 1-(2-Methylpropyl)-2-propyl-2H-pyrazolo[3,4-c]quinolin-4-amine, used as immunomodulators, for inducing or inhibiting cytokine biosynthesis in animals and in the treatment of viral and neoplastic diseases | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-02-01 | — | — | US | disclosed |
| US-20100274051-A1 | INFLAMMATORY CYTOKINE RELEASE INHIBITOR | INSTITUTE OF MEDICINAL MOLECULAR DESIGN. INC. (JP) | 2010-10-28 | — | — | US | disclosed |
| US-20090318435-A1 | PYRAZOLOPYRIDINES AND ANALOGS THEREOF | 3M INNOVATIVE PROPERTIES COMPANY | 2009-12-24 | — | — | US | disclosed |
| US-4840879-A | COLORED LATENT IMAGE IS REACTION PRODUCT OF COUPLER AND AROMATIC PRIMARY AMINO COLOR DEVELOPER | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1989-06-20 | — | — | US | disclosed |
| EP-0251419-B1 | FUEL COMPOSITION AND ADDITIVE CONCENTRATES, AND THEIR USE IN INHIBITING ENGINE COKING | ETHYL CORPORATION (US) | 1989-05-31 | — | — | EP | disclosed |
| EP-0113666-A1 | Hydroxybenzylcyclopentadienes and derivatives thereof | The B.F. GOODRICH Company (US) | 1984-07-18 | — | — | EP | disclosed |
| EP-0089101-A2 | Direct positive image-forming process | KONICA CORPORATION (JP) | 1983-09-21 | — | — | EP | disclosed |
| EP-0040741-B1 | PROCESS FOR THE PREPARATION OF CHLOROFORMIC-ACID ARYL ESTERS | BAYER AG (DE) | 1983-06-08 | — | — | EP | disclosed |
| US-4366102-A | Process for the preparation of chloroformic acid aryl esters | BAYER AKTIENGESELLSCHAFT (DE) | 1982-12-28 | — | — | US | disclosed |
| EP-0040741-A1 | Process for the preparation of chloroformic-acid aryl esters | BAYER AG (DE) | 1981-12-02 | — | — | EP | disclosed |
| US-3994724-A | SUBSTITUTED ANILINE PHOTOCONDUCTOR | SCOTT PAPER COMPANY (US) | 1976-11-30 | — | — | US | disclosed |
| US-3986991-A | EPOXIDES, TERTIARY AMINE, GLYCINE SALT | THE UPJOHN COMPANY (US) | 1976-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100274051-A1 | INFLAMMATORY CYTOKINE RELEASE INHIBITOR | IL1B, NFKBIA, IL1A | TDP1 4412/4885TP53 3038/4885PDE10A 2242/4885 |
| US-20120121651-A1 | PYRAZOLOPYRIDINES AND ANALOGS THEREOF | IL4, IL4I1, IL2 | TDP1 711/4885TP53 35/4885PDE10A 1548/4885 |
| US-20090318435-A1 | PYRAZOLOPYRIDINES AND ANALOGS THEREOF | IL4, IL2, IL4I1 | TDP1 1133/4885TP53 46/4885PDE10A 1926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.