Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | PDE1A | P54750 | 1/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17458967 | 0.96 | LMNA (0.44) | LMNAPKMNPBWR1SMN1; SMN2PTGS1 | |
| SCHEMBL17458974 | 0.87 | LMNA (0.35) | LMNASMN1; SMN2POLBL3MBTL1ALDH1A1 | |
| SCHEMBL16985416 | 0.84 | SMN1; SMN2 (0.38) | PKMSMN1; SMN2POLBL3MBTL1ALDH1A1 | |
| SCHEMBL17458949 | 0.84 | PKM (0.45) | LMNAPKMSMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL19170534 | 0.81 | LMNA (0.47) | LMNAPKMNPBWR1SMN1; SMN2PTGS1 | |
| SCHEMBL19163453 | 0.81 | MCOLN3 (0.40) | LMNAPKMSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL17458915 | 0.78 | GPR119 (0.44) | LMNAPKMALDH1A1 | |
| SCHEMBL2523142 | 0.76 | NPBWR1 (0.35) | PKMNPBWR1SMN1; SMN2PTGS2POLB | |
| SCHEMBL19170395 | 0.75 | LMNA (0.36) | LMNAPKMNPBWR1PTGS2 | |
| SCHEMBL16975468 | 0.74 | SMN1; SMN2 (0.41) | LMNAPKMSMN1; SMN2POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101066950-A | 4-amino-5-methylpyrazole derivatives and process for producing the same | SANKYO AGRO CO LTD (JP) | 2007-11-07 | — | — | CN | disclosed |
| CN-101062918-A | 4-amino-5-methylpyrazole derivatives and process for producing the same | SANKYO AGRO CO LTD (JP) | 2007-10-31 | — | — | CN | disclosed |
| CN-101062917-A | 4-amino-5-methylpyrazole derivatives and process for producing the same | SANKYO AGRO CO LTD (JP) | 2007-10-31 | — | — | CN | disclosed |
| CN-1732155-A | 4-amino-5-methylpyrazole derivatives and process for producing the same | SANKYO AGRO CO LTD (JP) | 2006-02-08 | — | — | CN | disclosed |
| EP-1580189-A1 | 4-AMINO-5-METHYLPYRAZOLE DERIVATIVES AND PROCESS FOR PRODUCTION THEREOF | Sankyo Agro Company, Limited (JP) | 2005-09-28 | — | — | EP | disclosed |