Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 4/20 | 0.34 |
| ▸ | CA1 | P00915 | 4/20 | 0.34 |
| ▸ | CA9 | Q16790 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156238 | 0.86 | CYSLTR2 (0.54) | CYSLTR2CYSLTR1HSP90AA1HSP90AB1KDM4E | |
| SCHEMBL6881332 | 0.83 | CYSLTR2 (0.42) | CYSLTR2CYSLTR1HSP90AA1HSP90AB1 | |
| SCHEMBL6155549 | 0.78 | FFAR1 (0.44) | CYSLTR2CYSLTR1HSP90AA1HSP90AB1CA12 | |
| SCHEMBL343105 | 0.78 | CA12 (0.40) | HSP90AA1HSP90AB1CA12CA1CA9 | |
| SCHEMBL15242469 | 0.77 | CA1 (0.42) | HSP90AA1HSP90AB1CA12CA1CA9 | |
| SCHEMBL6881287 | 0.76 | MEN1 (0.46) | SMN1; SMN2 | |
| SCHEMBL19745616 | 0.76 | CA12 (0.41) | HSP90AA1HSP90AB1CA12CA1CA9 | |
| SCHEMBL6156188 | 0.75 | ADRB1 (0.44) | RIPK1KDM4ERAB9A | |
| SCHEMBL6781597 | 0.74 | PNMT (0.48) | CA12CA1CA9KDM4E | |
| SCHEMBL3280559 | 0.74 | LMNA (0.43) | HSP90AA1HSP90AB1CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |