Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 8/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 8/20 | 0.42 |
| ▸ | PRKG1 | Q13976 | 5/20 | 0.40 |
| ▸ | PRKACA | P17612 | 4/20 | 0.40 |
| ▸ | GSK3A | P49840 | 3/20 | 0.40 |
| ▸ | GSK3B | P49841 | 3/20 | 0.40 |
| ▸ | PRKX | P51817 | 3/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | AKT2 | P31751 | 2/20 | 0.40 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.40 |
| ▸ | PRKG2 | Q13237 | 2/20 | 0.40 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.40 |
| ▸ | MINK1 | Q8N4C8 | 2/20 | 0.40 |
| ▸ | HIPK4 | Q8NE63 | 2/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6879525 | 0.88 | MEN1 (0.47) | MEN1KMT2AROCK1ROCK2PRKG1 | |
| SCHEMBL6155723 | 0.76 | CYSLTR2 (0.40) | SMN1; SMN2 | |
| SCHEMBL6881282 | 0.76 | POLB (0.43) | POLBALDH1A1HPGD | |
| SCHEMBL25846583 | 0.75 | KCNK2 (0.48) | MEN1KMT2AROCK1ROCK2PRKG1 | |
| SCHEMBL21288068 | 0.75 | KCNK2 (0.48) | MEN1KMT2AROCK1ROCK2PRKG1 | |
| SCHEMBL6879721 | 0.75 | ACACA (0.48) | KMT2AROCK1ROCK2CYP2C9CYP3A4 | |
| SCHEMBL22970326 | 0.74 | GPR139 (0.58) | MEN1KMT2AMAPK1GPR139POLB | |
| SCHEMBL21295101 | 0.74 | GPR139 (0.58) | MEN1KMT2AMAPK1GPR139POLB | |
| SCHEMBL6156238 | 0.74 | CYSLTR2 (0.54) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL24628720 | 0.73 | PTGS1 (0.50) | MEN1KMT2ACYP2D6HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |