Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 12/20 | 0.45 |
| ▸ | CES1 | P23141 | 10/20 | 0.44 |
| ▸ | CES2 | O00748 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23421922 | 0.78 | ALDH1A1 (0.39) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL8465400 | 0.76 | FAAH (0.43) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL9286604 | 0.72 | FAAH (0.32) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL9432450 | 0.71 | KDM4E (0.41) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL183178 | 0.71 | PLOD2 (0.46) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL11242744 | 0.70 | — | — | |
| SCHEMBL343124 | 0.70 | — | — | |
| SCHEMBL9588855 | 0.70 | — | — | |
| SCHEMBL9065118 | 0.70 | FAAH (0.38) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL1948056 | 0.69 | TDP1 (0.45) | FAAHCES1CES2MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9339531-B2 | Recognition of CYP2E1 epitopes | THE JOHNS HOPKINS UNIVERSITY (US) | 2016-05-17 | — | — | US | disclosed |
| US-20120040377-A1 | RECOGNITION OF CYP2E1 EPITOPES | THE JOHNS HOPKINS UNIVERSITY (US) | 2012-02-16 | — | — | US | disclosed |
| WO-2010099432-A2 | RECOGNITION OF CYP2E1 EPITOPES | THE JOHNS HOPKINS UNIVERSITY (US) | 2010-09-02 | — | — | WO | disclosed |