Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 12/20 | 0.43 |
| ▸ | CES1 | P23141 | 10/20 | 0.42 |
| ▸ | CES2 | O00748 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.39 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9065118 | 0.91 | FAAH (0.38) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL615589 | 0.76 | FAAH (0.45) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL183178 | 0.74 | PLOD2 (0.46) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL12582310 | 0.74 | — | — | |
| SCHEMBL6517983 | 0.72 | PLOD2 (0.44) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL9326020 | 0.72 | PLOD2 (0.44) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL9283764 | 0.72 | PLOD2 (0.44) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL6520648 | 0.72 | PLOD2 (0.44) | FAAHCES1CES2MEN1CYP1A2 | |
| Water SCHEMBL7191917 | 0.72 | PLOD2 (0.44) | FAAHCES1CES2MEN1CYP1A2 | |
| Water SCHEMBL7197275 | 0.72 | PLOD2 (0.44) | FAAHCES1CES2MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877210-A | CONTROLLING IMMUNE RESPONSE | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-02 | — | — | US | claimed |
| US-5583242-A | VANADYL COMPLEXES | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-10 | — | — | US | claimed |
| US-5565491-A | FOR TREATMENT OF DISEASES MARKED BY MALIGNANT PROLIFERATION OF B CELLS, SUCH AS LEUKEMIA AND LYMPHOMAS; ANTICARCINOGENIC AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-10-15 | — | — | US | claimed |
| EP-0448544-B1 | Process for preparation of fluoromethyl-substituted piperidine carbodithioates | ROHM & HAAS (US) | 1996-07-03 | — | — | EP | claimed |
| EP-0448544-A2 | Process for preparation of fluoromethyl-substituted piperidine carbodithioates | ROHM AND HAAS COMPANY (US) | 1991-09-25 | — | — | EP | claimed |
| US-4785129-A | Methyl 4,4,4-trifluoro-3-oxo-butanethioate | MONSANTO COMPANY (US) | 1988-11-15 | — | — | US | claimed |
| US-20230241078-A1 | Vanadyl and vanadate for use in reducing stress-induced metabolic derangement | CFM PHARMA HOLDING B.V. (NL) | 2023-08-03 | — | — | US | disclosed |
| US-20200246352-A1 | Vanadyl and vanadate for use in reducing stress-induced metabolic derangement | CFM PHARMA HOLDING B.V. (NL) | 2020-08-06 | — | — | US | disclosed |
| EP-3412654-A1 | PROCESSES FOR THE MANUFACTURE OF HALOALKYL PYRIMIDYL COMPOUNDS, AND COMPOUNDS USEFUL IN THEIR MANUFACTURE | SOLVAY SA (BE) | 2018-12-12 | — | — | EP | disclosed |
| US-5877210-A | CONTROLLING IMMUNE RESPONSE | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-02 | — | — | US | disclosed |
| US-5846998-A | Use of phosphotyrosine phosphatase inhibitors or phosphotyrosine kinase activators for controlling cellular proliferation | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-12-08 | — | — | US | disclosed |
| US-5693627-A | TREATING DISEASES SUCH AS LEUKEMIAS AND LYMPHOMAS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-12-02 | — | — | US | disclosed |
| US-5583242-A | VANADYL COMPLEXES | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-10 | — | — | US | disclosed |
| EP-0448541-A2 | Process for preparation of fluoromethyl-substituted pyridine carbodithioates | ROHM AND HAAS COMPANY (US) | 1991-09-25 | — | — | EP | disclosed |
| EP-0448543-A2 | Process for preparation of fluoromethyl-substituted pyridine carbodithioates | ROHM AND HAAS COMPANY (US) | 1991-09-25 | — | — | EP | disclosed |
| EP-0448544-A2 | Process for preparation of fluoromethyl-substituted piperidine carbodithioates | ROHM AND HAAS COMPANY (US) | 1991-09-25 | — | — | EP | disclosed |
| EP-0448542-A2 | Process for preparation of fluoromethyl-substituted dihydropyridine carbodithioates | ROHM AND HAAS COMPANY (US) | 1991-09-25 | — | — | EP | disclosed |
| US-5051512-A | Reaction of trifluoroacetic acid thiomethyl ester and ammonia, reaction with an alkyl aldehyde and heating | MONSANTO COMPANY (US) | 1991-09-24 | — | — | US | disclosed |
| US-4785129-A | Methyl 4,4,4-trifluoro-3-oxo-butanethioate | MONSANTO COMPANY (US) | 1988-11-15 | — | — | US | disclosed |
| US-4785129-A | Methyl 4,4,4-trifluoro-3-oxo-butanethioate | MONSANTO COMPANY (US) | 1988-11-15 | — | — | US | disclosed |