Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 4/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155892 | 0.76 | MAOB (0.58) | PRKDC | |
| SCHEMBL6157332 | 0.70 | ALDH1A1 (0.33) | — | |
| SCHEMBL3601316 | 0.70 | ADRA2C (0.42) | — | |
| SCHEMBL28365890 | 0.67 | KMT2A (0.62) | PRKDCPDE3BPDE3A | |
| SCHEMBL1449846 | 0.66 | ADRA2C (0.50) | — | |
| SCHEMBL31060159 | 0.66 | PRKDC (1.00) | PRKDC | |
| SCHEMBL6156974 | 0.64 | ERAP1 (0.58) | PRKDCPDE3BPDE3A | |
| SCHEMBL6156448 | 0.64 | PRKDC (0.64) | PRKDCPDE3BPDE3A | |
| SCHEMBL16344358 | 0.64 | MAPT (0.35) | — | |
| SCHEMBL3588890 | 0.63 | ADRA2C (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894805-B1 | Ribose substituted aromatic derivatives, their preparation and use as medicaments | AVENTIS PHARMA SA (FR) | 2005-02-09 | — | — | EP | claimed |