Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | FHIT | P49789 | 1/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156007 | 0.82 | HSP90AA1 (0.45) | MAOBHSP90AA1PSMD14MMP2BLM | |
| SCHEMBL6158795 | 0.73 | HPGD (0.42) | MAOBHSP90AA1PSMD14MMP2BLM | |
| SCHEMBL6156963 | 0.72 | PDE3B (0.45) | — | |
| SCHEMBL7166211 | 0.69 | POLB (0.40) | KMT2AMEN1KDM4EALDH1A1LMNA | |
| SCHEMBL7235676 | 0.65 | ALDH1A1 (0.42) | NPC1RAB9ATDP1KMT2AMEN1 | |
| SCHEMBL6156025 | 0.62 | MAOB (0.55) | MAOBKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL10187364 | 0.62 | KMT2A (0.33) | KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL30887675 | 0.62 | RAB9A (0.56) | MAOBNPC1RAB9ATDP1KMT2A | |
| SCHEMBL10187365 | 0.61 | KMT2A (0.34) | KMT2AMEN1ALDH1A1GAAMAPK1 | |
| SCHEMBL19019871 | 0.61 | KDM4E (0.51) | HSP90AA1RXFP1NPC1RAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894805-B1 | Ribose substituted aromatic derivatives, their preparation and use as medicaments | AVENTIS PHARMA SA (FR) | 2005-02-09 | — | — | EP | disclosed |
| US-5968939-A | ANTIBIOTICS FROM AMINOOXOBENZOPYRAN COMPOUNDS | HOECHST MARION ROUSSEL (FR) | 1999-10-19 | — | — | US | disclosed |
| EP-0894805-A1 | Ribose substituted aromatic derivatives, their preparation and use as medicaments | HOECHST MARION ROUSSEL (FR) | 1999-02-03 | — | — | EP | disclosed |