Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.45 |
| ▸ | PRKDC | P78527 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156007 | 0.80 | HSP90AA1 (0.45) | — | |
| SCHEMBL6158795 | 0.75 | HPGD (0.42) | — | |
| SCHEMBL6155934 | 0.72 | MAOB (0.43) | — | |
| SCHEMBL6155892 | 0.71 | MAOB (0.58) | PRKDC | |
| SCHEMBL5347182 | 0.68 | PDE3B (0.66) | PDE3BPDE3APRKDC | |
| SCHEMBL5340254 | 0.65 | PDE3B (0.71) | PDE3BPDE3APRKDC | |
| SCHEMBL5342355 | 0.65 | PDE3B (0.63) | PDE3BPDE3APRKDC | |
| SCHEMBL6156411 | 0.65 | PRKDC (0.49) | PDE3BPDE3APRKDC | |
| SCHEMBL6155495 | 0.64 | MAOB (0.51) | PDE3BPDE3APRKDC | |
| SCHEMBL28365890 | 0.64 | KMT2A (0.62) | PDE3BPDE3APRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894805-B1 | Ribose substituted aromatic derivatives, their preparation and use as medicaments | AVENTIS PHARMA SA (FR) | 2005-02-09 | — | — | EP | disclosed |
| US-5968939-A | ANTIBIOTICS FROM AMINOOXOBENZOPYRAN COMPOUNDS | HOECHST MARION ROUSSEL (FR) | 1999-10-19 | — | — | US | disclosed |
| EP-0894805-A1 | Ribose substituted aromatic derivatives, their preparation and use as medicaments | HOECHST MARION ROUSSEL (FR) | 1999-02-03 | — | — | EP | disclosed |