Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | AHR | P35869 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156178 | 0.85 | ALDH1A1 (0.36) | ALDH1A1LMNASMN1; SMN2MAPTHPGD | |
| SCHEMBL273282 | 0.84 | ALDH1A1 (0.47) | ALDH1A1ESR1AHRLMNASMN1; SMN2 | |
| SCHEMBL8751920 | 0.83 | NQO1 (0.46) | ALDH1A1ESR1AHRSMN1; SMN2KDM4E | |
| SCHEMBL1262690 | 0.82 | ALDH1A1 (0.56) | ALDH1A1LMNASMN1; SMN2MAPTHPGD | |
| SCHEMBL30833931 | 0.82 | MAOA (0.55) | ALDH1A1SMN1; SMN2KDM4EMAOAMAOB | |
| SCHEMBL8111540 | 0.82 | MAOA (0.55) | ALDH1A1SMN1; SMN2KDM4EMAOAMAOB | |
| SCHEMBL6154744 | 0.81 | ESR1 (0.39) | ESR1AHRPTPN1NQO1 | |
| SCHEMBL1486859 | 0.80 | NPC1 (0.39) | ALDH1A1ESR1AHRLMNASMN1; SMN2 | |
| SCHEMBL6156181 | 0.80 | BCHE (0.32) | — | |
| SCHEMBL5883815 | 0.79 | ALDH1A1 (0.47) | ALDH1A1ESR1AHRLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |