Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156111 | 0.92 | SMN1; SMN2 (0.37) | LMNAMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6155148 | 0.83 | HIF1A (0.40) | LMNAMAPTSMN1; SMN2 | |
| SCHEMBL6155140 | 0.83 | HIF1A (0.40) | LMNAMAPTSMN1; SMN2 | |
| SCHEMBL6156122 | 0.82 | LMNA (0.31) | LMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL6157925 | 0.78 | CNR1 (0.31) | — | |
| SCHEMBL6156949 | 0.77 | HIF1A (0.38) | LMNAMAPTSMN1; SMN2OPRM1 | |
| SCHEMBL6156942 | 0.77 | HIF1A (0.38) | LMNAMAPTSMN1; SMN2OPRM1 | |
| SCHEMBL6158217 | 0.74 | — | — | |
| SCHEMBL6156363 | 0.71 | SLC9A1 (0.34) | LMNASMN1; SMN2 | |
| SCHEMBL6156925 | 0.70 | HIF1A (0.41) | LMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6348627-B1 | CONTROLLING PHYTOPATHOGENIC FUNGI | DOW AGROSCIENCES LLC | 2002-02-19 | — | — | US | claimed |
| EP-1286955-B1 | ARYL AND HETEROARYLCYCLOPROPYL OXIME ETHERS AND THEIR USE AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2005-02-02 | — | — | EP | disclosed |
| EP-1286955-A1 | ARYL AND HETEROARYLCYCLOPROPYL OXIME ETHERS AND THEIR USE AS FUNGICIDES | Dow AgroSciences LLC (US) | 2003-03-05 | — | — | EP | disclosed |
| US-6348627-B1 | CONTROLLING PHYTOPATHOGENIC FUNGI | DOW AGROSCIENCES LLC | 2002-02-19 | — | — | US | disclosed |
| WO-2001087826-A1 | ARYL AND HETEROARYLCYCLOPROPYL OXIME ETHERS AND THEIR USE AS FUNGICIDES | ROHM AND HAAS COMPANY (US) | 2001-11-22 | — | — | WO | disclosed |