⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8706560 | 0.83 | — | — | |
| SCHEMBL6066328 | 0.81 | OPRM1 (0.39) | — | |
| SCHEMBL3739903 | 0.78 | DNM1 (0.36) | — | |
| SCHEMBL12475355 | 0.73 | — | — | |
| SCHEMBL378171 | 0.71 | — | — | |
| SCHEMBL573231 | 0.71 | — | — | |
| SCHEMBL464424 | 0.71 | — | — | |
| SCHEMBL4606903 | 0.71 | — | — | |
| SCHEMBL378172 | 0.71 | — | — | |
| SCHEMBL269384 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501845-A1 | ANTIBACTERIAL COMPOUNDS WITH IMPROVED PHARMACOKINETIC PROFILES | Abbott Laboratories (US) | 2005-02-02 | — | — | EP | disclosed |
| EP-1501847-A2 | 11-DEOXY AZALIDE ANTIBACTERIALS | Abbott Laboratories (US) | 2005-02-02 | — | — | EP | disclosed |
| EP-1501519-A1 | 9-OXIME MACROLIDE ANTIBACTERIALS | Abbott Laboratories (US) | 2005-02-02 | — | — | EP | disclosed |
| EP-1501846-A1 | TRICYCLIC MACROLIDE ANTIBACTERIAL COMPOUNDS | Abbott Laboratories (US) | 2005-02-02 | — | — | EP | disclosed |
| EP-1499326-A1 | OXOLIDE ANTIBACTERIALS | Abbott Laboratories (US) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003093288-A1 | ANTIBACTERIAL COMPOUNDS WITH IMPROVED PHARMACOKINETIC PROFILES | ABBOTT LABORATORIES (US) | 2003-11-13 | — | — | WO | disclosed |
| WO-2003093289-A1 | TRICYCLIC MACROLIDE ANTIBACTERIAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2003-11-13 | — | — | WO | disclosed |
| WO-2003090761-A1 | 9-OXIME MACROLIDE ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2003-11-06 | — | — | WO | disclosed |
| WO-2003090679-A2 | 11-DEOXY AZALIDE ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2003-11-06 | — | — | WO | disclosed |
| WO-2003090760-A1 | OXOLIDE ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2003-11-06 | — | — | WO | disclosed |
| EP-0073443-B1 | 2H-1,2,4,6-THIATRIAZINE-1,1 DIOXIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | BASF Aktiengesellschaft (DE) | 1986-11-05 | — | — | EP | disclosed |