Sugi Predict

Sugi Predict / Compounds / SCHEMBL526160

SCHEMBL526160

SCHEMBL526160

O=C(NCCc1ncc(C(F)(F)F)cc1Cl)c1c(Cl)cccc1Cl

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ GLA P06280 1/20 0.59
▸ KMT2A Q03164 6/20 0.59
▸ MEN1 O00255 5/20 0.59
▸ MAPT P10636 3/20 0.59
▸ NPSR1 Q6W5P4 2/20 0.59
▸ SMN1; SMN2 Q16637 1/20 0.59
▸ CYP1A2 P05177 2/20 0.50
▸ CYP3A4 P08684 2/20 0.50
▸ CYP2D6 P10635 2/20 0.50
▸ CYP2C19 P33261 2/20 0.50
▸ CYP2C9 P11712 1/20 0.50
▸ ALDH1A1 P00352 1/20 0.49
▸ P2RX7 Q99572 2/20 0.48
▸ HTT P42858 1/20 0.47
▸ RAB9A P51151 1/20 0.47
▸ POLB P06746 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29797174 1.00 GLA (0.59) GLAKMT2AMEN1MAPTNPSR1
SCHEMBL15286566 0.88 KMT2A (0.61) GLAKMT2AMEN1MAPTNPSR1
SCHEMBL29356683 0.88 KMT2A (0.61) GLAKMT2AMEN1MAPTNPSR1
SCHEMBL21950 0.88 KMT2A (0.61) GLAKMT2AMEN1MAPTNPSR1
SCHEMBL4456238 0.86 GLA (0.65) GLAKMT2AMEN1MAPTCYP1A2
Fluopyram SCHEMBL29353266 0.85 GLA (0.59) GLAKMT2AMEN1MAPTNPSR1
Fluopyram SCHEMBL67230 0.85 GLA (0.59) GLAKMT2AMEN1MAPTNPSR1
SCHEMBL6888143 0.84 POLB (0.46) GLAKMT2AMEN1SMN1; SMN2ALDH1A1
SCHEMBL876739 0.83 P2RX7 (0.43) GLAKMT2AMEN1MAPTNPSR1
SCHEMBL16363567 0.82 GLA (0.56) GLAKMT2AMEN1MAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2645856-A1 USE OF FLUOPYRAM FOR CONTROLLING NEMATODES IN CROPS AND FOR INCREASING YIELD Bayer Intellectual Property GmbH (DE) 2013-10-09 — — EP claimed
US-20130253018-A1 Use of Fluopyram for Controlling Nematodes in Crops and for Increasing Yield BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-09-26 — — US claimed
US-20130232645-A1 USE OF ACTIVE INGREDIENTS FOR CONTROLLING NEMATODES IN NEMATODE-RESISTANT CROPS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-09-05 — — US claimed
WO-2012072660-A1 USE OF FLUOPYRAM FOR CONTROLLING NEMATODES IN CROPS AND FOR INCREASING YIELD BAYER CROPSCIENCE AG (DE) 2012-06-07 — — WO claimed
EP-2460406-A1 Use of fluopyram for controlling nematodes in nematode resistant crops Bayer CropScience AG (DE) 2012-06-06 — — EP claimed
JP-4782418-B2 — — 2011-09-28 — — JP claimed
US-7572818-B2 Fungicides; N-{2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]ethyl}-2-trifluoromethylbenzamide; -{2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]ethyl}-2-iodobenzamide; -{2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]ethyl}-2-bromobenzamide BAYER CROPSCIENCE S.A. (FR) 2009-08-11 — — US claimed
EP-1531673-B1 NOVEL 2-PYRIDYLETHYLBENZAMIDE DERIVATIVE BAYER CROPSCIENCE SA (FR) 2006-01-04 — — EP claimed
US-20050234110-A1 Novel 2-pyridylethylbenzamide derivative BAYER SAS (FR) 2005-10-20 — — US claimed
EP-1531673-A2 NOVEL 2-PYRIDYLETHYLBENZAMIDE DERIVATIVE Bayer CropScience S.A. (FR) 2005-05-25 — — EP claimed
WO-2004016088-A2 NOVEL 2-PYRIDYLETHYLBENZAMIDE DERIVATIVE BAYER CROPSCIENCE S.A. (FR) 2004-02-26 — — WO claimed
EP-1389614-A1 Novel N-[2-(2-Pyridyl)ethyl]benzamide derivatives as fungicides Bayer CropScience S.A. (FR) 2004-02-18 — — EP claimed
CN-109952028-B Fluopyram-containing formulations for controlling nematodes 拜耳作物科学股份公司 2022-05-27 — — CN disclosed
CN-109952028-B Fluopyram-containing formulations for controlling nematodes 拜耳作物科学股份公司 2022-05-27 — — CN disclosed
US-11241010-B2 Use of succinate dehydrogenase inhibitors for extending shelf life of fruits and vegetables BAYER INTELLECTUAL PROPERTY GMBH (DE) 2022-02-08 — — US disclosed
EP-3509420-B1 FORMULATIONS CONTAINING FLUOPYRAM FOR THE CONTROL OF NEMATODES BAYER CROPSCIENCE AG (DE) 2022-01-05 — — EP disclosed
WO-2004016088-A2 NOVEL 2-PYRIDYLETHYLBENZAMIDE DERIVATIVE BAYER CROPSCIENCE S.A. (FR) 2004-02-26 — — WO disclosed
WO-2004016088-A2 NOVEL 2-PYRIDYLETHYLBENZAMIDE DERIVATIVE BAYER CROPSCIENCE S.A. (FR) 2004-02-26 — — WO disclosed
EP-1389614-A1 Novel N-[2-(2-Pyridyl)ethyl]benzamide derivatives as fungicides Bayer CropScience S.A. (FR) 2004-02-18 — — EP disclosed
EP-1389614-A1 Novel N-[2-(2-Pyridyl)ethyl]benzamide derivatives as fungicides Bayer CropScience S.A. (FR) 2004-02-18 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050234110-A1 Novel 2-pyridylethylbenzamide derivative PNPO, PAH, CNPY2 GLA 1133/4885KMT2A 1827/4885MEN1 4496/4885
US-20130253018-A1 Use of Fluopyram for Controlling Nematodes in Crops and for Increasing Yield PNPO, PNMT, PFAS GLA 2713/4885KMT2A 972/4885MEN1 4752/4885
US-20130232645-A1 USE OF ACTIVE INGREDIENTS FOR CONTROLLING NEMATODES IN NEMATODE-RESISTANT CROPS MLN, ACHE, NANP GLA 2729/4885KMT2A 2020/4885MEN1 4791/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.