Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 4/20 | 0.38 |
| ▸ | NOS2 | P35228 | 3/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.34 |
| ▸ | VDR | P11473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156487 | 0.86 | CYSLTR2 (0.50) | CYP4F2CYP4A11PPARGPPARAFFAR1 | |
| SCHEMBL6878844 | 0.84 | MTNR1A (0.41) | MTNR1AMTNR1BFFAR1CYSLTR2CYSLTR1 | |
| SCHEMBL2107016 | 0.83 | VDR (0.48) | NOS1NOS2CYP4F2CYP4A11MGLL | |
| SCHEMBL6884926 | 0.80 | FFAR1 (0.34) | FFAR1VDR | |
| SCHEMBL6155762 | 0.79 | CYSLTR2 (0.36) | CYP4F2CYP4A11FFAR1MAOBCYSLTR2 | |
| SCHEMBL6155133 | 0.79 | CYSLTR2 (0.37) | FFAR1CYSLTR2CYSLTR1VDR | |
| SCHEMBL6885983 | 0.76 | CYP3A4 (0.46) | MTNR1AMTNR1BPPARGPPARA | |
| SCHEMBL2107635 | 0.76 | MGLL (0.46) | CYP4F2CYP4A11MGLLPPARGPPARA | |
| SCHEMBL2107020 | 0.75 | CYP4F2 (0.46) | CYP4F2CYP4A11MGLLPPARGPPARA | |
| SCHEMBL6155252 | 0.74 | MAOB (0.52) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |