Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.49 |
| ▸ | DBH | P09172 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10628077 | 0.86 | EGLN1 (0.47) | APLNRDBHALDH1A1MAPTEGLN1 | |
| SCHEMBL27629672 | 0.81 | CA1 (0.41) | DBHALDH1A1CA2PDE4B | |
| SCHEMBL23120458 | 0.80 | APLNR (0.48) | APLNRALDH1A1MAPTCA2TSHR | |
| SCHEMBL6156795 | 0.78 | CMA1 (0.53) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL27871199 | 0.76 | MAPT (0.60) | MAPTMEN1KMT2APOLB | |
| SCHEMBL5259359 | 0.74 | APLNR (0.48) | APLNRALDH1A1MAPTEGLN1KDM4E | |
| SCHEMBL9804694 | 0.72 | KDM4E (0.61) | APLNRALDH1A1MAPTTSHRKDM4E | |
| SCHEMBL8175132 | 0.72 | LMNA (0.56) | APLNRALDH1A1MAPTEGLN1TSHR | |
| SCHEMBL13486597 | 0.72 | GSK3A (0.58) | APLNRALDH1A1MAPTCA2TSHR | |
| SCHEMBL8331084 | 0.71 | LMNA (0.57) | APLNRALDH1A1MAPTEGLN1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832071-B1 | 1,3-DIHYDRO-2H-IMIDAZOL-2-ONE DERIVATIVES HAVING PDE IV AND CYTOKININ INHIBITING ACTIVITY | JANSSEN PHARMACEUTICA NV (BE) | 2005-09-28 | — | — | EP | disclosed |
| US-5869515-A | TREATING ASTHMATIC OR ATOPIC DISEASES | JANSSEN PHARMACEUTICA N.V. (BE) | 1999-02-09 | — | — | US | disclosed |