Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.53 |
| ▸ | CCR5 | P51681 | 7/20 | 0.53 |
| ▸ | DRD2 | P14416 | 5/20 | 0.49 |
| ▸ | DRD4 | P21917 | 5/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8211043 | 0.91 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3CCR5DRD2 | |
| SCHEMBL6160574 | 0.82 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3CCR5DRD2 | |
| SCHEMBL6162549 | 0.79 | DRD2 (0.71) | SLC6A2SLC6A4SLC6A3DRD2DRD4 | |
| SCHEMBL8208853 | 0.78 | LTA4H (0.53) | SLC6A2SLC6A4SLC6A3DRD2 | |
| SCHEMBL6160069 | 0.78 | LTA4H (0.53) | SLC6A2SLC6A4SLC6A3DRD2 | |
| SCHEMBL8220653 | 0.77 | SLC18A3 (0.43) | CCR5DRD2 | |
| SCHEMBL6160819 | 0.76 | DRD2 (0.55) | SLC6A2SLC6A4SLC6A3CCR5DRD2 | |
| SCHEMBL3900031 | 0.76 | DRD2 (0.56) | SLC6A2SLC6A4SLC6A3DRD2DRD4 | |
| SCHEMBL3900030 | 0.76 | DRD2 (0.56) | SLC6A2SLC6A4SLC6A3DRD2DRD4 | |
| SCHEMBL3891405 | 0.75 | CCR5 (0.48) | SLC6A2SLC6A4SLC6A3CCR5DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755923-B1 | Ameliorant or remedy for symptoms caused by Ischemic diseases and Phenylpiperidine compounds useful therefor | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2005-05-04 | — | — | EP | disclosed |
| US-6469010-B1 | COMPOSITION ALSO FOR ALLEVIATION OR TREATMENT OF SYMPTOMS DERIVED FROM SEIZURES, EPILEPSY AND MIGRAINE HEADACHES, AND SUPPRESSION OF CALCIUM ION OVERLOAD | SUNTORY LIMITED (JP) | 2002-10-22 | — | — | US | disclosed |
| US-6048876-A | ANTICONVULSANTS; ANTIEPILEPIC AGENT | SUNTORY LIMITED (JP) | 2000-04-11 | — | — | US | disclosed |
| EP-0755923-A1 | AMELIORANT OR REMEDY FOR SYMPTOMS CAUSED BY ISCHEMIC DISEASES AND COMPOUNDS USEFUL THEREFOR | SUNTORY LIMITED (JP) | 1997-01-29 | — | — | EP | disclosed |